Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P61222 Abce1 ATP-binding cassette sub-family E member … Mus musculus (Mouse) 599 aa

Protein Details: P61222 (Abce1)

Protein Information
AccessionP61222
Protein NamesATP-binding cassette sub-family E member 1 (RNase L inhibitor) (EC 3.6.5.-) (Ribonuclease 4 inhibitor) (RNS4I)
Gene SymbolAbce1
OrganismMus musculus (Mouse)
Length599 aa
IsoformsNo isoforms
Related PMIDs 28526873 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADKLTRIAI11VNHDKCKPKK21CRQECKKSCP31VVRMGKLCIE41VTPQSKIAWI
51-10051SETLCIGCGI61CIKKCPFGAL71SIVNLPSNLE81KETTHRYCAN91AFKLHRLPIP
101-150101RPGEVLGLVG111TNGIGKSTAL121KILAGKQKPN131LGKYDDPPDW141QEILTYFRGS
151-200151ELQNYFTKIL161EDDLKAIIKP171QYVDQIPKAA181KGTVGSILDR191KDETKTQAIV
201-250201CQQLDLTHLK211ERNVEDLSGG221ELQRFACAVV231CIQKADIFMF241DEPSSYLDVK
251-300251QRLKAAITIR261SLINPDRYII271VVEHDLSVLD281YLSDFICCLY291GVPSAYGVVT
301-350301MPFSVREGIN311IFLDGYVPTE321NLRFRDASLV331FKVAETANEE341EVKKMCMYKY
351-400351PGMKKKMGEF361ELAIVAGEFT371DSEIMVMLGE381NGTGKTTFIR391MLAGRLKPDE
401-450401GGEVPVLNVS411YKPQKISPKS421TGSVRQLLHE431KIRDAYTHPQ441FVTDVMKPLQ
451-500451IENIIDQEVQ461TLSGGELQRV471ALALCLGKPA481DVYLIDEPSA491YLDSEQRLMA
501-550501ARVVKRFILH511AKKTAFVVEH521DFIMATYLAD531RVIVFDGVPS541KNTVANSPQT
551-599551LLAGMNKFLS561QLEITFRRDP571NNYRPRINKL581NSIKDVEQKK591SGNYFFLDD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
16 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.69
Deep-Palm: 0.22
21 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
Deep-Palm: 0.45
25 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.79
Deep-Palm: 0.55
29 RLI1 RNase L inhibitor RLI-like, possible metal-binding domain - -
GPS-Palm: 0.87
Deep-Palm: 0.73
38 4Fe-4S ferredoxins P-loop containing nucleoside triphosphate hydrolase 4Fe-4S ferredoxin-type, iron-sulphur binding domain RLI1 Possible Fer4-like domain in RNase L inhibitor, RLI
MLE (39008777)
-
GPS-Palm: 0.93
Deep-Palm: 0.89
55 - - -
GPS-Palm: 0.95
Deep-Palm: 0.90
58 - - -
GPS-Palm: 0.77
Deep-Palm: 0.91
61 - - -
GPS-Palm: 0.80
Deep-Palm: 0.90
65 4Fe-4S dicluster domain
brain (39008777)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.85
Deep-Palm: 0.95
88 - - -
GPS-Palm: 0.77
Deep-Palm: 0.85
201 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
brain (39008777)
MLE (39008777)
Brain (35358180)
GPS-Palm: 0.75
Deep-Palm: 0.95
227 ABC transporter
MLE (39008777)
-
GPS-Palm: 0.93
Deep-Palm: 0.94
231 ABC transporter
MLE (39008777)
-
GPS-Palm: 0.79
Deep-Palm: 0.93
287 - - -
Deep-Palm: 0.91
288 - - -
Deep-Palm: 0.84
346 - - -
GPS-Palm: 0.79
Deep-Palm: 0.52
475 - - -
GPS-Palm: 0.92
Deep-Palm: 0.98
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.200
4/4 (100.0%)
1
Brain
Specificity: 0.050
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
15
Brain tissue (Mass)
Specificity: 0.750
15/56 (26.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine