Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P61620 | Sec61a1 | Protein transport protein Sec61 subunit … | Mus musculus (Mouse) | 476 aa |
Protein Details: P61620 (Sec61a1)
Protein Information
| Accession | P61620 |
|---|---|
| Protein Names | Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1) |
| Gene Symbol | Sec61a1 |
| Organism | Mus musculus (Mouse) |
| Length | 476 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29733200 34884899 35477839 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAIKFLEVIK11PFCVILPEIQ21KPERKIQFKE31KVLWTAITLF41IFLVCCQIPL
51-10051FGIMSSDSAD61PFYWMRVILA71SNRGTLMELG81ISPIVTSGLI91MQLLAGAKII
101-150101EVGDTPKDRA111LFNGAQKLFG121MIITIGQSIV131YVMTGMYGDP141SEMGAGICLL
151-200151ITIQLFVAGL161IVLLLDELLQ171KGYGLGSGIS181LFIATNICET191IVWKAFSPTT
201-250201VNTGRGMEFE211GAIIALFHLL221ATRTDKVRAL231REAFYRQNLP241NLMNLIATIF
251-300251VFAVVIYFQG261FRVDLPIKSA271RYRGQYNTYP281IKLFYTSNIP291IILQSALVSN
301-350301LYVISQMLSA311RFSGNLLVSL321LGTWSDTSSG331GPARAYPVGG341LCYYLSPPES
351-400351FGSVLEDPVH361AVVYIVFMLG371SCAFFSKTWI381EVSGSSAKDV391AKQLKEQQMV
401-450401MRGHRETSMV411HELNRYIPTA421AAFGGLCIGA431LSVLADFLGA441IGSGTGILLA
451-476451VTIIYQYFEI461FVKEQSEVGS471MGALLF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | SWISSPALM DBPTM CYSMODDB | SecY domain superfamily |
Liver
(28526873)
| - |
GPS-Palm: 0.92
Deep-Palm: 0.47
|
| 45 | Translocon Sec61/SecY, plug domain SecY domain superfamily SecY/SEC61-alpha family | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.36
|
|
| 46 | Translocon Sec61/SecY, plug domain SecY domain superfamily SecY/SEC61-alpha family | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.39
|
|
| 148 | - | - | - |
Deep-Palm: 0.94
|
|
| 188 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.60
|
|
| 342 | - | - | - |
Deep-Palm: 0.97
|
|
| 372 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.32
|
|
| 427 | - | - | - |
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Liver
Specificity: 0.667
6/6 (100.0%)
2
Testis
Specificity: 0.222
2/2 (100.0%)
1
Brain
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.