Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P61769 | B2M | Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form … | Homo sapiens (Human) | 119 aa |
Protein Details: P61769 (B2M)
Protein Information
| Accession | P61769 |
|---|---|
| Protein Names | Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3] |
| Gene Symbol | B2M |
| Organism | Homo sapiens (Human) |
| Length | 119 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRSVALAVL11ALLSLSGLEA21IQRTPKIQVY31SRHPAENGKS41NFLNCYVSGF
51-10051HPSDIEVDLL61KNGERIEKVE71HSDLSFSKDW81SFYLLYYTEF91TPTEKDEYAC
101-119101RVNHVTLSQP111KIVKWDRDM
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 45 | SWISSPALM DBPTM CYSMODDB | Immunoglobulin-like fold Immunoglobulin C1-set domain Immunoglobulin-like domain Immunoglobulin-like domain superfamily Major Histocompatibility Complex/Immunoglobulin Immunoglobulin C1-set | - | - |
Deep-Palm: 0.19
|
| 100 | - | - | - |
Deep-Palm: 0.56
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 16 | S → C | 0.002545 | SNP | Missense Mutation | GBM |
| 46 | Y → Cfs*10 | 0.027027 | DEL | Frame Shift Del | DLBC |
| 46 | Y → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 46 | Y → Cfs*10 | 0.005435 | DEL | Frame Shift Del | ESCA |
| 74 | L → Cfs*29 | 0.001969 | DEL | Frame Shift Del | HNSC |
| 100 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.001014 | SNP | Missense Mutation | BRCA |
| 100* | C → ? | 0.002033 | INS | Nonsense Mutation | THCA |