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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P61981 YWHAG 14-3-3 protein gamma (Protein kinase … Homo sapiens (Human) 247 aa

Protein Details: P61981 (YWHAG)

Protein Information
Accession P61981
Protein Names 14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene Symbol YWHAG
Organism Homo sapiens (Human)
Length 247 aa
Isoforms No isoforms
Related PMIDs 19137006 19801377 21076176 29733200 31251020 32944167 36430497 37611173
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.412
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
21
LNCaP cells
Specificity: 0.412
21/46 (45.7%)
11
Jurkat T cells
Specificity: 0.216
11/25 (44.0%)
10
HAP1 cells
Specificity: 0.196
10/10 (100.0%)
4
PC3 cells
Specificity: 0.078
4/4 (100.0%)
4
Cerebral cortex
Specificity: 0.078
4/4 (100.0%)
1
DU145 cells
Specificity: 0.020
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MVDREQLVQK11ARLAEQAERY21DDMAAAMKNV31TELNEPLSNE41ERNLLSVAYK
51-10051NVVGARRSSW61RVISSIEQKT71SADGNEKKIE81MVRAYREKIE91KELEAVCQDV
101-150101LSLLDNYLIK111NCSETQYESK121VFYLKMKGDY131YRYLAEVATG141EKRATVVESS
151-200151EKAYSEAHEI161SKEHMQPTHP171IRLGLALNYS181VFYYEIQNAP191EQACHLAKTA
201-247201FDDAIAELDT211LNEDSYKDST221LIMQLLRDNL231TLWTSDQQDD241DGGEGNN
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
97 Experimental Prediction (Low) 14-3-3 protein 37611173
112 Prediction (Low) - -
194 Prediction (Low) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
46 S → C 0.001014 SNP Missense Mutation BRCA
57 R → C 0.002294 SNP Missense Mutation OV
58 S → C 0.002427 SNP Missense Mutation BLCA
97 C → S 0.002294 SNP Missense Mutation OV
97* C → ? 0.004219 SNP Nonsense Mutation SARC