Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62069 | Usp46 | Ubiquitin carboxyl-terminal hydrolase 46 (EC … | Mus musculus (Mouse) | 366 aa |
Protein Details: P62069 (Usp46)
Protein Information
| Accession | P62069 |
|---|---|
| Protein Names | Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) |
| Gene Symbol | Usp46 |
| Organism | Mus musculus (Mouse) |
| Length | 366 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTVRNIASIC11NMGTNASALE21KDIGPEQFPI31NEHYFGLVNF41GNTCYCNSVL
51-10051QALYFCRPFR61ENVLAYKAQQ71KKKENLLTCL81ADLFHSIATQ91KKKVGVIPPK
101-150101KFISRLRKEN111DLFDNYMQQD121AHEFLNYLLN131TIADILQEEK141KQEKQNGKLK
151-200151NGNMNEPAEN161NKPELTWVHE171IFQGTLTNET181RCLNCETVSS191KDEDFLDLSV
201-250201DVEQNTSITH211CLRDFSNTET221LCSEQKYYCE231TCCSKQEAQK241RMRVKKLPMI
251-300251LALHLKRFKY261MEQLHRYTKL271SYRVVFPLEL281RLFNTSSDAV291NLDRMYDLVA
301-350301VVVHCGSGPN311RGHYITIVKS321HGFWLLFDDD331IVEKIDAQAI341EEFYGLTSDI
351-366351SKNSESGYIL361FYQSRE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | SWISSPALM DBPTM CYSMODDB | - |
Forebrain
(28680068)
| - |
GPS-Palm: 0.74
Deep-Palm: 0.05
|
| 44 | Ubiquitin carboxyl-terminal hydrolases Ubiquitin specific protease domain Cysteine proteinases Peptidase C19, ubiquitin carboxyl-terminal hydrolase Papain-like cysteine peptidase superfamily | - | - |
Deep-Palm: 0.02
|
|
| 46 | Peptidase C19, ubiquitin carboxyl-terminal hydrolase Ubiquitin specific protease domain Cysteine proteinases Papain-like cysteine peptidase superfamily | - | - |
Deep-Palm: 0.03
|
|
| 56 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.17
|
|
| 79 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.92
|
|
| 182 | - | - | - |
Deep-Palm: 0.08
|
|
| 185 | - | - | - |
Deep-Palm: 0.32
|
|
| 211 | - | - | - |
Deep-Palm: 0.37
|
|
| 222 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.03
|
|
| 229 | - | - | - |
Deep-Palm: 0.04
|
|
| 232 | - | - | - |
Deep-Palm: 0.09
|
|
| 233 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.13
|
|
| 305 | - | - | - |
Deep-Palm: 0.17
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.222
2/2 (100.0%)
1
Brain
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Brain tissue (Mass)
Specificity: 0.667
6/56 (10.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.