Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62079 | TSPAN5 | Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane … | Homo sapiens (Human) | 268 aa |
Protein Details: P62079 (TSPAN5)
Protein Information
| Accession | P62079 |
|---|---|
| Protein Names | Tetraspanin-5 (Tspan-5) (Tetraspan NET-4) (Transmembrane 4 superfamily member 9) |
| Gene Symbol | TSPAN5 |
| Organism | Homo sapiens (Human) |
| Length | 268 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSGKHYKGPE11VSCCIKYFIF21GFNVIFWFLG31ITFLGIGLWA41WNEKGVLSNI
51-10051SSITDLGGFD61PVWLFLVVGG71VMFILGFAGC81IGALRENTFL91LKFFSVFLGI
101-150101IFFLELTAGV111LAFVFKDWIK121DQLYFFINNN131IRAYRDDIDL141QNLIDFTQEY
151-200151WQCCGAFGAD161DWNLNIYFNC171TDSNASRERC181GVPFSCCTKD191PAEDVINTQC
201-250201GYDARQKPEV211DQQIVIYTKG221CVPQFEKWLQ231DNLTIVAGIF241IGIALLQIFG
251-268251ICLAQNLVSD261IEAVRASW
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | SWISSPALM | - | - | - |
Deep-Palm: 0.04
|
| 14 | SWISSPALM | - | - | - |
Deep-Palm: 0.17
|
| 80 | SWISSPALM | Tetraspanin family | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.98
|
| 153 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.16
|
|
| 154 | - | - | - |
Deep-Palm: 0.17
|
|
| 170 | - | - | - |
Deep-Palm: 0.07
|
|
| 180 | - | - | - |
Deep-Palm: 0.19
|
|
| 186 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.60
|
|
| 187 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.55
|
|
| 200 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.33
|
|
| 221 | - | - | - |
Deep-Palm: 0.59
|
|
| 252 | SWISSPALM | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 1.000
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 80 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |
| 80 | C → Y | 0.002976 | SNP | Missense Mutation | KIRC |
| 187 | C → Y | 0.006993 | SNP | Missense Mutation | LAML |
| 221 | C → G | 0.002288 | SNP | Missense Mutation | STAD |