Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P62141 Ppp1cb Serine/threonine-protein phosphatase PP1-beta catalytic subunit … Mus musculus (Mouse) 327 aa

Protein Details: P62141 (Ppp1cb)

Protein Information
AccessionP62141
Protein NamesSerine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (EC 3.1.3.16) (EC 3.1.3.53)
Gene SymbolPpp1cb
OrganismMus musculus (Mouse)
Length327 aa
IsoformsNo isoforms
Related PMIDs 29660268 29733200 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADGELNVDS11LITRLLEVRG21CRPGKIVQMT31EAEVRGLCIK41SREIFLSQPI
51-10051LLELEAPLKI61CGDIHGQYTD71LLRLFEYGGF81PPEANYLFLG91DYVDRGKQSL
101-150101ETICLLLAYK111IKYPENFFLL121RGNHECASIN131RIYGFYDECK141RRFNIKLWKT
151-200151FTDCFNCLPI161AAIVDEKIFC171CHGGLSPDLQ181SMEQIRRIMR191PTDVPDTGLL
201-250201CDLLWSDPDK211DVQGWGENDR221GVSFTFGADV231VSKFLNRHDL241DLICRAHQVV
251-300251EDGYEFFAKR261QLVTLFSAPN271YCGEFDNAGG281MMSVDETLMC291SFQILKPSEK
301-327301KAKYQYGGLN311SGRPVTPPRT321ANPPKKR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
21 Serine-threonine protein phosphatase, N-terminal - -
GPS-Palm: 0.88
Deep-Palm: 0.97
38 Serine-threonine protein phosphatase, N-terminal Metallo-dependent phosphatase-like - -
GPS-Palm: 0.71
Deep-Palm: 0.97
61 - -
Brain (35358180)
Deep-Palm: 0.93
104 - -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.93
Deep-Palm: 0.68
126 Calcineurin-like phosphoesterase
Brain (34200797)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.77
Deep-Palm: 0.18
139 - -
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.13
154 - -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.91
Deep-Palm: 0.32
157 - -
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.07
170 SWISSPALM DBPTM CYSMODDB Calcineurin-like phosphoesterase
Forebrain (28680068)
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.59
171 SWISSPALM DBPTM CYSMODDB Calcineurin-like phosphoesterase
Forebrain (28680068)
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.72
201 - -
Brain (35358180)
Deep-Palm: 0.88
244 - -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.80
Deep-Palm: 0.89
272 - - -
Deep-Palm: 0.65
290 - - -
Deep-Palm: 0.77
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
4
Brain
Specificity: 0.133
4/4 (100.0%)
2
Testis
Specificity: 0.067
2/2 (100.0%)
1
Liver
Specificity: 0.033
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
23
Brain tissue (Mass)
Specificity: 0.767
23/56 (41.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine