Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62195 | PSMC5 | 26S proteasome regulatory subunit 8 … | Homo sapiens (Human) | 406 aa |
Protein Details: P62195 (PSMC5)
Protein Information
| Accession | P62195 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG) |
| Gene Symbol | PSMC5 |
| Organism | Homo sapiens (Human) |
| Length | 406 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 32944167 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MALDGPEQME11LEEGKAGSGL21RQYYLSKIEE31LQLIVNDKSQ41NLRRLQAQRN
51-10051ELNAKVRLLR61EELQLLQEQG71SYVGEVVRAM81DKKKVLVKVH91PEGKFVVDVD
101-150101KNIDINDVTP111NCRVALRNDS121YTLHKILPNK131VDPLVSLMMV141EKVPDSTYEM
151-200151IGGLDKQIKE161IKEVIELPVK171HPELFEALGI181AQPKGVLLYG191PPGTGKTLLA
201-250201RAVAHHTDCT211FIRVSGSELV221QKFIGEGARM231VRELFVMARE241HAPSIIFMDE
251-300251IDSIGSSRLE261GGSGGDSEVQ271RTMLELLNQL281DGFEATKNIK291VIMATNRIDI
301-350301LDSALLRPGR311IDRKIEFPPP321NEEARLDILK331IHSRKMNLTR341GINLRKIAEL
351-400351MPGASGAEVK361GVCTEAGMYA371LRERRVHVTQ381EDFEMAVAKV391MQKDSEKNMS
401-406401IKKLWK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 112 | - | - | - |
Deep-Palm: 0.32
|
|
| 209 | - | - | - |
Deep-Palm: 0.97
|
|
| 363 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
2
PC3
Specificity: 0.500
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.250
1/1 (100.0%)
1
293T cell
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 57 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 57 | R → C | 0.014599 | SNP | Missense Mutation | READ |
| 112 | C → C | 0.001887 | SNP | Silent | UCEC |
| 310 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |