Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62258-2 | YWHAE | 14-3-3 protein epsilon (14-3-3E) | Homo sapiens (Human) | 233 aa |
Protein Details: P62258-2 (YWHAE)
Protein Information
| Accession | P62258-2 |
|---|---|
| Protein Names | 14-3-3 protein epsilon (14-3-3E) |
| Gene Symbol | YWHAE |
| Organism | Homo sapiens (Human) |
| Length | 233 aa |
| Isoforms | |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVESMKKVAG11MDVELTVEER21NLLSVAYKNV31IGARRASWRI41ISSIEQKEEN
51-10051KGGEDKLKMI61REYRQMVETE71LKLICCDILD81VLDKHLIPAA91NTGESKVFYY
101-150101KMKGDYHRYL111AEFATGNDRK121EAAENSLVAY131KAASDIAMTE141LPPTHPIRLG
151-200151LALNFSVFYY161EILNSPDRAC171RLAKAAFDDA181IAELDTLSEE191SYKDSTLIMQ
201-233201LLRDNLTLWT211SDMQGDGEEQ221NKEALQDVED231ENQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 75 | - |
HeLa
(29575903)
| - | - | |
| 76 | - |
HeLa
(29575903)
| - | - | |
| 97 | - | - | - |
Deep-Palm: 0.90
|
|
| 98 | - | - | - |
Deep-Palm: 0.88
|
|
| 192 | - | - | - |
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 152 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |