Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62259 | Ywhae | 14-3-3 protein epsilon (14-3-3E) | Mus musculus (Mouse) | 255 aa |
Protein Details: P62259 (Ywhae)
Protein Information
| Accession | P62259 |
|---|---|
| Protein Names | 14-3-3 protein epsilon (14-3-3E) |
| Gene Symbol | Ywhae |
| Organism | Mus musculus (Mouse) |
| Length | 255 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDDREDLVYQ11AKLAEQAERY21DEMVESMKKV31AGMDVELTVE41ERNLLSVAYK
51-10051NVIGARRASW61RIISSIEQKE71ENKGGEDKLK81MIREYRQMVE91TELKLICCDI
101-150101LDVLDKHLIP111AANTGESKVF121YYKMKGDYHR131YLAEFATGND141RKEAAENSLV
151-200151AYKAASDIAM161TELPPTHPIR171LGLALNFSVF181YYEILNSPDR191ACRLAKAAFD
201-250201DAIAELDTLS211EESYKDSTLI221MQLLRDNLTL231WTSDMQGDGE241EQNKEALQDV
251-255251EDENQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 97 | SWISSPALM DBPTM CYSMODDB | 14-3-3 protein |
Brain
(34200797)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.87
Deep-Palm: 0.90
|
| 98 | SWISSPALM DBPTM CYSMODDB | 14-3-3 protein |
Brain
(34200797)
Forebrain
(28680068)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.84
Deep-Palm: 0.88
|
| 192 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.120
6/6 (100.0%)
5
Brain
Specificity: 0.100
5/5 (100.0%)
2
Testis
Specificity: 0.040
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
37
Brain tissue (Mass)
Specificity: 0.740
37/56 (66.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.