Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62280 | RPS11 | Small ribosomal subunit protein uS17 … | Homo sapiens (Human) | 158 aa |
Protein Details: P62280 (RPS11)
Protein Information
| Accession | P62280 |
|---|---|
| Protein Names | Small ribosomal subunit protein uS17 (40S ribosomal protein S11) |
| Gene Symbol | RPS11 |
| Organism | Homo sapiens (Human) |
| Length | 158 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 31251020 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADIQTERAY11QKQPTIFQNK21KRVLLGETGK31EKLPRYYKNI41GLGFKTPKEA
51-10051IEGTYIDKKC61PFTGNVSIRG71RILSGVVTKM81KMQRTIVIRR91DYLHYIRKYN
101-150101RFEKRHKNMS111VHLSPCFRDV121QIGDIVTVGE131CRPLSKTVRF141NVLKVTKAAG
151-158151TKKQFQKF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 60 | SWISSPALM DBPTM CYSMODDB | Ribosomal S17 N-terminal | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.94
|
| 116 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.82
|
|
| 131 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S17 |
SW480 cell line
(26865113)
|
cerebral cortex
(36430497)
|
GPS-Palm: 0.92
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
cerebral cortex
Specificity: 0.286
4/4 (100.0%)
2
LNCaP
Specificity: 0.143
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.143
2/2 (100.0%)
1
293T cell
Specificity: 0.071
1/1 (100.0%)
1
HUVECs
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Cerebral Cortex (Mass)
Specificity: 0.214
3/4 (75.0%)
1
LNCaP cells (Mass)
Specificity: 0.071
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 36 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 105 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 139 | R → C | 0.002506 | SNP | Missense Mutation | COAD |