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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P62333 PSMC6; SUG2 26S proteasome regulatory subunit 10B … Homo sapiens (Human) 389 aa

Protein Details: P62333 (PSMC6)

Protein Information
Accession P62333
Protein Names 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene Symbol PSMC6; SUG2
Organism Homo sapiens (Human)
Length 389 aa
Isoforms No isoforms
Related PMIDs 19137006 29733200 32944167
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.312
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
5
Jurkat T cells
Specificity: 0.312
5/25 (20.0%)
4
HAP1 cells
Specificity: 0.250
4/10 (40.0%)
4
293T cells
Specificity: 0.250
4/10 (40.0%)
3
PC3 cells
Specificity: 0.188
3/4 (75.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MADPRDKALQ11DYRKKLLEHK21EIDGRLKELR31EQLKELTKQY41EKSENDLKAL
51-10051QSVGQIVGEV61LKQLTEEKFI71VKATNGPRYV81VGCRRQLDKS91KLKPGTRVAL
101-150101DMTTLTIMRY111LPREVDPLVY121NMSHEDPGNV131SYSEIGGLSE141QIRELREVIE
151-200151LPLTNPELFQ161RVGIIPPKGC171LLYGPPGTGK181TLLARAVASQ191LDCNFLKVVS
201-250201SSIVDKYIGE211SARLIREMFN221YARDHQPCII231FMDEIDAIGG241RRFSEGTSAD
251-300251REIQRTLMEL261LNQMDGFDTL271HRVKMIMATN281RPDTLDPALL291RPGRLDRKIH
301-350301IDLPNEQARL311DILKIHAGPI321TKHGEIDYEA331IVKLSDGFNG341ADLRNVCTEA
351-389351GMFAIRADHD361FVVQEDFMKA371VRKVADSKKL381ESKLDYKPV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
83 Prediction (Medium) - -
170 Prediction (Medium) - -
193 Prediction (Medium) - -
347 Prediction (High) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
161 R → C 0.001887 SNP Missense Mutation UCEC
177 G → C 0.002427 SNP Missense Mutation BLCA
213 R → C 0.001887 SNP Missense Mutation UCEC
241 R → C 0.001887 SNP Missense Mutation UCEC
291 R → C 0.003460 SNP Missense Mutation CESC
356 R → C 0.002141 SNP Missense Mutation SKCM