Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62333 | PSMC6 | 26S proteasome regulatory subunit 10B … | Homo sapiens (Human) | 389 aa |
Protein Details: P62333 (PSMC6)
Protein Information
| Accession | P62333 |
|---|---|
| Protein Names | 26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42) |
| Gene Symbol | PSMC6 |
| Organism | Homo sapiens (Human) |
| Length | 389 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MADPRDKALQ11DYRKKLLEHK21EIDGRLKELR31EQLKELTKQY41EKSENDLKAL
51-10051QSVGQIVGEV61LKQLTEEKFI71VKATNGPRYV81VGCRRQLDKS91KLKPGTRVAL
101-150101DMTTLTIMRY111LPREVDPLVY121NMSHEDPGNV131SYSEIGGLSE141QIRELREVIE
151-200151LPLTNPELFQ161RVGIIPPKGC171LLYGPPGTGK181TLLARAVASQ191LDCNFLKVVS
201-250201SSIVDKYIGE211SARLIREMFN221YARDHQPCII231FMDEIDAIGG241RRFSEGTSAD
251-300251REIQRTLMEL261LNQMDGFDTL271HRVKMIMATN281RPDTLDPALL291RPGRLDRKIH
301-350301IDLPNEQARL311DILKIHAGPI321TKHGEIDYEA331IVKLSDGFNG341ADLRNVCTEA
351-389351GMFAIRADHD361FVVQEDFMKA371VRKVADSKKL381ESKLDYKPV
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 83 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.97
|
|
| 170 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.97
|
|
| 193 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 228 | - | - | - |
Deep-Palm: 0.23
|
|
| 347 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
293T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 161 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 177 | G → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 213 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 241 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 291 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 356 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |