Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62424 | RPL7A | Large ribosomal subunit protein eL8 … | Homo sapiens (Human) | 266 aa |
Protein Details: P62424 (RPL7A)
Protein Information
| Accession | P62424 |
|---|---|
| Protein Names | Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (PLA-X polypeptide) (Surfeit locus protein 3) |
| Gene Symbol | RPL7A |
| Organism | Homo sapiens (Human) |
| Length | 266 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MPKGKKAKGK11KVAPAPAVVK21KQEAKKVVNP31LFEKRPKNFG41IGQDIQPKRD
51-10051LTRFVKWPRY61IRLQRQRAIL71YKRLKVPPAI81NQFTQALDRQ91TATQLLKLAH
101-150101KYRPETKQEK111KQRLLARAEK121KAAGKGDVPT131KRPPVLRAGV141NTVTTLVENK
151-200151KAQLVVIAHD161VDPIELVVFL171PALCRKMGVP181YCIIKGKARL191GRLVHRKTCT
201-250201TVAFTQVNSE211DKGALAKLVE221AIRTNYNDRY231DEIRRHWGGN241VLGPKSVARI
251-266251AKLEKAKAKE261LATKLG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 174 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.91
|
|
| 182 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.97
|
|
| 199 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family | - |
Unknown
(32651440)
|
GPS-Palm: 0.84
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.300
3
PC3
Specificity: 0.300
3/3 (100.0%)
2
LNCaP
Specificity: 0.200
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.200
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.200
2/2 (100.0%)
1
293T cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 175 | R → C | 0.002288 | SNP | Missense Mutation | STAD |