Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62424 | RPL7A; SURF-3; SURF3 | Large ribosomal subunit protein eL8 … | Homo sapiens (Human) | 266 aa |
Protein Details: P62424 (RPL7A)
Protein Information
| Accession | P62424 |
|---|---|
| Protein Names | Large ribosomal subunit protein eL8 (60S ribosomal protein L7a) (PLA-X polypeptide) (Surfeit locus protein 3) |
| Gene Symbol | RPL7A; SURF-3; SURF3 |
| Organism | Homo sapiens (Human) |
| Length | 266 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.558
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
24
LNCaP cells
Specificity: 0.558
24/46 (52.2%)
10
HAP1 cells
Specificity: 0.233
10/10 (100.0%)
4
293T cells
Specificity: 0.093
4/10 (40.0%)
3
PC3 cells
Specificity: 0.070
3/4 (75.0%)
2
Cerebral cortex
Specificity: 0.047
2/4 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MPKGKKAKGK11KVAPAPAVVK21KQEAKKVVNP31LFEKRPKNFG41IGQDIQPKRD
51-10051LTRFVKWPRY61IRLQRQRAIL71YKRLKVPPAI81NQFTQALDRQ91TATQLLKLAH
101-150101KYRPETKQEK111KQRLLARAEK121KAAGKGDVPT131KRPPVLRAGV141NTVTTLVENK
151-200151KAQLVVIAHD161VDPIELVVFL171PALCRKMGVP181YCIIKGKARL191GRLVHRKTCT
201-250201TVAFTQVNSE211DKGALAKLVE221AIRTNYNDRY231DEIRRHWGGN241VLGPKSVARI
251-266251AKLEKAKAKE261LATKLG
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 174 | Prediction (Low) | - | - |
| 182 | Prediction (High) | - | - |
| 199 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Ribosomal protein L7Ae/L30e/S12e/Gadd45 family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 175 | R → C | 0.002288 | SNP | Missense Mutation | STAD |