Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62631 | Eef1a2 | Elongation factor 1-alpha 2 (EF-1-alpha-2) … | Mus musculus (Mouse) | 463 aa |
Protein Details: P62631 (Eef1a2)
Protein Information
| Accession | P62631 |
|---|---|
| Protein Names | Elongation factor 1-alpha 2 (EF-1-alpha-2) (EC 3.6.5.-) (Eukaryotic elongation factor 1 A-2) (eEF1A-2) (Statin-S1) |
| Gene Symbol | Eef1a2 |
| Organism | Mus musculus (Mouse) |
| Length | 463 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29575903 29733200 31311849 34200797 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGKEKTHINI11VVIGHVDSGK21STTTGHLIYK31CGGIDKRTIE41KFEKEAAEMG
51-10051KGSFKYAWVL61DKLKAERERG71ITIDISLWKF81ETTKYYITII91DAPGHRDFIK
101-150101NMITGTSQAD111CAVLIVAAGV121GEFEAGISKN131GQTREHALLA141YTLGVKQLIV
151-200151GVNKMDSTEP161AYSEKRYDEI171VKEVSAYIKK181IGYNPATVPF191VPISGWHGDN
201-250201MLEPSPNMPW211FKGWKVERKE221GNASGVSLLE231ALDTILPPTR241PTDKPLRLPL
251-300251QDVYKIGGIG261TVPVGRVETG271ILRPGMVVTF281APVNITTEVK291SVEMHHEALS
301-350301EALPGDNVGF311NVKNVSVKDI321RRGNVCGDSK331ADPPQEAAQF341TSQVIILNHP
351-400351GQISAGYSPV361IDCHTAHIAC371KFAELKEKID381RRSGKKLEDN391PKSLKSGDAA
401-450401IVEMVPGKPM411CVESFSQYPP421LGRFAVRDMR431QTVAVGVIKN441VEKKSGGAGK
451-463451VTKSAQKAQK461AGK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 31 | Translational (tr)-type GTP-binding domain P-loop containing nucleoside triphosphate hydrolase Translation factor GTPase superfamily members | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.96
|
|
| 111 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.73
Deep-Palm: 0.92
|
|
| 326 | - |
Brain
(31311849)
|
Brain
(31311849)
|
Deep-Palm: 0.86
|
|
| 363 | GTP-eEF1A C-terminal domain-like |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.56
|
|
| 370 | GTP-eEF1A C-terminal domain-like |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.77
|
|
| 411 | SWISSPALM DBPTM CYSMODDB | GTP-eEF1A C-terminal domain-like |
Forebrain
(28680068)
|
Brain
(35358180)
|
GPS-Palm: 0.75
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Brain
Specificity: 0.129
4/4 (100.0%)
1
Raw 264.7
Specificity: 0.032
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.654
17
Brain tissue (Mass)
Specificity: 0.548
17/56 (30.4%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.290
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.