Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62737 | Acta2 | Actin, aortic smooth muscle (EC … | Mus musculus (Mouse) | 377 aa |
Protein Details: P62737 (Acta2)
Protein Information
| Accession | P62737 |
|---|---|
| Protein Names | Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form] |
| Gene Symbol | Acta2 |
| Organism | Mus musculus (Mouse) |
| Length | 377 aa |
| Isoforms | No isoforms |
| Related PMIDs | 34200797 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCEEEDSTAL11VCDNGSGLCK21AGFAGDDAPR31AVFPSIVGRP41RHQGVMVGMG
51-10051QKDSYVGDEA61QSKRGILTLK71YPIEHGIITN81WDDMEKIWHH91SFYNELRVAP
101-150101EEHPTLLTEA111PLNPKANREK121MTQIMFETFN131VPAMYVAIQA141VLSLYASGRT
151-200151TGIVLDSGDG161VTHNVPIYEG171YALPHAIMRL181DLAGRDLTDY191LMKILTERGY
201-250201SFVTTAEREI211VRDIKEKLCY221VALDFENEMA231TAASSSSLEK241SYELPDGQVI
251-300251TIGNERFRCP261ETLFQPSFIG271MESAGIHETT281YNSIMKCDID291IRKDLYANNV
301-350301LSGGTTMYPG311IADRMQKEIT321ALAPSTMKIK331IIAPPERKYS341VWIGGSILAS
351-377351LSTFQQMWIS361KQEYDEAGPS371IVHRKCF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.02
|
|
| 12 | ATPase, nucleotide binding domain Actin family | - | - |
Deep-Palm: 0.11
|
|
| 19 | ATPase, nucleotide binding domain Actin family | - | - |
Deep-Palm: 0.94
|
|
| 219 | Actin |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.71
Deep-Palm: 0.91
|
|
| 259 | - | - | - |
Deep-Palm: 0.65
|
|
| 287 | - | - | - |
Deep-Palm: 0.31
|
|
| 376 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
4
Liver
Specificity: 0.364
4/4 (100.0%)
2
Brain
Specificity: 0.182
2/2 (100.0%)
2
Testis
Specificity: 0.182
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.273
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.