Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62805 | H4C1; H4/A; H4FA; HIST1H4A; H4C2; H4/I; H4FI; HIST1H4B; H4C3; H4/G; H4FG; HIST1H4C; H4C4; H4/B; H4FB; HIST1H4D; H4C5; H4/J; H4FJ; HIST1H4E; H4C6; H4/C; H4FC; HIST1H4F; H4C8; H4/H; H4FH; HIST1H4H; H4C9; H4/M; H4FM; HIST1H4I; H4C11; H4/E; H4FE; HIST1H4J; H4C12; H4/D; H4FD; HIST1H4K; H4C13; H4/K; H4FK; HIST1H4L; H4C14; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A; H4C15; H4/O; H4FO; HIST2H4B; H4C16; H4-16; HIST4H4 | Histone H4 | Homo sapiens (Human) | 103 aa |
Protein Details: P62805 (H4C1)
Protein Information
| Accession | P62805 |
|---|---|
| Protein Names | Histone H4 |
| Gene Symbol | H4C1; H4/A; H4FA; HIST1H4A; H4C2; H4/I; H4FI; HIST1H4B; H4C3; H4/G; H4FG; HIST1H4C; H4C4; H4/B; H4FB; HIST1H4D; H4C5; H4/J; H4FJ; HIST1H4E; H4C6; H4/C; H4FC; HIST1H4F; H4C8; H4/H; H4FH; HIST1H4H; H4C9; H4/M; H4FM; HIST1H4I; H4C11; H4/E; H4FE; HIST1H4J; H4C12; H4/D; H4FD; HIST1H4K; H4C13; H4/K; H4FK; HIST1H4L; H4C14; H4/N; H4F2; H4FN; HIST2H4; HIST2H4A; H4C15; H4/O; H4FO; HIST2H4B; H4C16; H4-16; HIST4H4 |
| Organism | Homo sapiens (Human) |
| Length | 103 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 22496122 25914232 29733200 31251020 31382980 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.581
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.581
36/46 (78.3%)
10
HAP1 cells
Specificity: 0.161
10/10 (100.0%)
4
293T cells
Specificity: 0.065
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.065
4/4 (100.0%)
2
Jurkat T cells
Specificity: 0.032
2/25 (8.0%)
2
PC3 cells
Specificity: 0.032
2/4 (50.0%)
2
CEMx174 cells
Specificity: 0.032
2/3 (66.7%)
1
U937 cells
Specificity: 0.016
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.016
1/2 (50.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSGRGKGGKG11LGKGGAKRHR21KVLRDNIQGI31TKPAIRRLAR41RGGVKRISGL
51-10051IYEETRGVLK61VFLENVIRDA71VTYTEHAKRK81TVTAMDVVYA91LKRQGRTLYG
101-103101FGG
Palmitoylation Sites Details
No known palmitoylation sites
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 10 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 15 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 18 | R → C | 0.002294 | SNP | Missense Mutation | OV |
| 18 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 18 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 19 | H → Cfs*31 | 0.003460 | DEL | Frame Shift Del | CESC |
| 20 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 29 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 29 | G → C | 0.002506 | SNP | Missense Mutation | COAD |
| 36 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 37 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 37 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 40 | R → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 40 | R → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 40 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 41 | R → C | 0.012195 | SNP | Missense Mutation | MESO |
| 41 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 48 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 52 | Y → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 52 | Y → C | 0.005435 | SNP | Missense Mutation | ESCA |
| 56 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 56 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 56 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 62 | F → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 73 | Y → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 73 | Y → C | 0.002288 | SNP | Missense Mutation | STAD |
| 89 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 93 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 93 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 95 | G → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 96 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 100 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 102 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 103 | G → C | 0.002020 | SNP | Missense Mutation | PRAD |
| ? | ? → ? | 0.001764 | SNP | Missense Mutation | LUAD |
| ? | ? → ? | 0.001969 | SNP | Missense Mutation | HNSC |
| ? | ? → ? | 0.002427 | SNP | Missense Mutation | BLCA |
| ? | ? → ? | 0.002294 | SNP | Missense Mutation | OV |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |
| ? | ? → ? | 0.002020 | SNP | Missense Mutation | PRAD |
| ? | ? → ? | 0.004219 | SNP | Missense Mutation | SARC |
| ? | ? → ? | 0.002288 | SNP | Missense Mutation | STAD |
| ? | ? → ? | 0.002020 | SNP | Missense Mutation | PRAD |
| ? | ? → ? | 0.008130 | SNP | Missense Mutation | THYM |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |