Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62826 | RAN; ARA24; OK/SW-cl.81 | GTP-binding nuclear protein Ran (EC … | Homo sapiens (Human) | 216 aa |
Protein Details: P62826 (RAN)
Protein Information
| Accession | P62826 |
|---|---|
| Protein Names | GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein) |
| Gene Symbol | RAN; ARA24; OK/SW-cl.81 |
| Organism | Homo sapiens (Human) |
| Length | 216 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 21076176 22496122 29733200 31251020 36430497 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.583
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
35
LNCaP cells
Specificity: 0.583
35/46 (76.1%)
10
HAP1 cells
Specificity: 0.167
10/10 (100.0%)
4
Jurkat T cells
Specificity: 0.067
4/25 (16.0%)
4
293T cells
Specificity: 0.067
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.067
4/4 (100.0%)
2
DU145 cells
Specificity: 0.033
2/2 (100.0%)
1
Endothelial cells
Specificity: 0.017
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAQGEPQVQ11FKLVLVGDGG21TGKTTFVKRH31LTGEFEKKYV41ATLGVEVHPL
51-10051VFHTNRGPIK61FNVWDTAGQE71KFGGLRDGYY81IQAQCAIIMF91DVTSRVTYKN
101-150101VPNWHRDLVR111VCENIPIVLC121GNKVDIKDRK131VKAKSIVFHR141KKNLQYYDIS
151-200151AKSNYNFEKP161FLWLARKLIG171DPNLEFVAMP181ALAPPEVVMD191PALAAQYEHD
201-216201LEVAQTTALP211DEDDDL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 85 | Prediction (Low) | - | - |
| 112 | CYSMODDB SWISSPALM DBPTM | Ras family | - |
| 120 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | Ras family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 85 | C → C | 0.002033 | SNP | Silent | LUSC |