Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62829 | RPL23 | Large ribosomal subunit protein uL14 … | Homo sapiens (Human) | 140 aa |
Protein Details: P62829 (RPL23)
Protein Information
| Accession | P62829 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL14 (60S ribosomal protein L17) (60S ribosomal protein L23) |
| Gene Symbol | RPL23 |
| Organism | Homo sapiens (Human) |
| Length | 140 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 32944167 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSKRGRGGSS11GAKFRISLGL21PVGAVINCAD31NTGAKNLYII41SVKGIKGRLN
51-10051RLPAAGVGDM61VMATVKKGKP71ELRKKVHPAV81VIRQRKSYRR91KDGVFLYFED
101-140101NAGVIVNNKG111EMKGSAITGP121VAKECADLWP131RIASNAGSIA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 28 | SWISSPALM DBPTM CYSMODDB | Large ribosomal subunit protein uL14 superfamily Large ribosomal subunit protein uL14 |
SW480 cell line
(26865113)
HeLa
(29575903)
|
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.91
Deep-Palm: 0.96
|
| 125 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein L14p/L23e | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.286
2
LNCaP
Specificity: 0.222
2/2 (100.0%)
2
HAP1 cell
Specificity: 0.222
2/2 (100.0%)
2
PC3
Specificity: 0.222
2/2 (100.0%)
1
293T cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Cerebral Cortex (Mass)
Specificity: 0.222
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 58 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |