Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62906 | RPL10A; NEDD6 | Large ribosomal subunit protein uL1 … | Homo sapiens (Human) | 217 aa |
Protein Details: P62906 (RPL10A)
Protein Information
| Accession | P62906 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL1 (60S ribosomal protein L10a) (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6) |
| Gene Symbol | RPL10A; NEDD6 |
| Organism | Homo sapiens (Human) |
| Length | 217 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 29733200 31251020 31382980 32944167 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.353
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
12
LNCaP cells
Specificity: 0.353
12/46 (26.1%)
10
HAP1 cells
Specificity: 0.294
10/10 (100.0%)
4
PC3 cells
Specificity: 0.118
4/4 (100.0%)
4
293T cells
Specificity: 0.118
4/10 (40.0%)
2
DU145 cells
Specificity: 0.059
2/2 (100.0%)
1
Jurkat T cells
Specificity: 0.029
1/25 (4.0%)
1
U937 cells
Specificity: 0.029
1/1 (100.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSSKVSRDTL11YEAVREVLHG21NQRKRRKFLE31TVELQISLKN41YDPQKDKRFS
51-10051GTVRLKSTPR61PKFSVCVLGD71QQHCDEAKAV81DIPHMDIEAL91KKLNKNKKLV
101-150101KKLAKKYDAF111LASESLIKQI121PRILGPGLNK131AGKFPSLLTH141NENMVAKVDE
151-200151VKSTIKFQMK161KVLCLAVAVG171HVKMTDDELV181YNIHLAVNFL191VSLLKKNWQN
201-217201VRALYIKSTM211GKPQRLY
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 66 | CYSMODDB SWISSPALM DBPTM | - | - |
| 74 | Experimental CYSMODDB SWISSPALM DBPTM | - | 19801377 |
| 164 | CYSMODDB SWISSPALM DBPTM Prediction (High) | Ribosomal protein L1p/L10e family | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 164 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |