Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P62906 | RPL10A | Large ribosomal subunit protein uL1 … | Homo sapiens (Human) | 217 aa |
Protein Details: P62906 (RPL10A)
Protein Information
| Accession | P62906 |
|---|---|
| Protein Names | Large ribosomal subunit protein uL1 (60S ribosomal protein L10a) (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6) |
| Gene Symbol | RPL10A |
| Organism | Homo sapiens (Human) |
| Length | 217 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31251020 31382980 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSKVSRDTL11YEAVREVLHG21NQRKRRKFLE31TVELQISLKN41YDPQKDKRFS
51-10051GTVRLKSTPR61PKFSVCVLGD71QQHCDEAKAV81DIPHMDIEAL91KKLNKNKKLV
101-150101KKLAKKYDAF111LASESLIKQI121PRILGPGLNK131AGKFPSLLTH141NENMVAKVDE
151-200151VKSTIKFQMK161KVLCLAVAVG171HVKMTDDELV181YNIHLAVNFL191VSLLKKNWQN
201-217201VRALYIKSTM211GKPQRLY
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 66 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.97
|
| 74 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.67
|
| 164 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein L1p/L10e family | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
HAP1 cell
Specificity: 0.400
2/2 (100.0%)
1
LNCaP
Specificity: 0.200
1/1 (100.0%)
1
U937 cell
Specificity: 0.200
1/1 (100.0%)
1
293T cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 164 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |