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UniProt ID Gene Symbol Protein Name Organism Length Action
P62917 RPL8 Large ribosomal subunit protein uL2 … Homo sapiens (Human) 257 aa

Protein Details: P62917 (RPL8)

Protein Information
AccessionP62917
Protein NamesLarge ribosomal subunit protein uL2 (60S ribosomal protein L8)
Gene SymbolRPL8
OrganismHomo sapiens (Human)
Length257 aa
IsoformsNo isoforms
Related PMIDs 29733200 31251020 36430497
Database SourcesdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGRVIRGQRK11GAGSVFRAHV21KHRKGAARLR31AVDFAERHGY41IKGIVKDIIH
51-10051DPGRGAPLAK61VVFRDPYRFK71KRTELFIAAE81GIHTGQFVYC91GKKAQLNIGN
101-150101VLPVGTMPEG111TIVCCLEEKP121GDRGKLARAS131GNYATVISHN141PETKKTRVKL
151-200151PSGSKKVISS161ANRAVVGVVA171GGGRIDKPIL181KAGRAYHKYK191AKRNCWPRVR
201-250201GVAMNPVEHP211FGGGNHQHIG221KPSTIRRDAP231AGRKVGLIAA241RRTGRLRGTK
251-257251TVQEKEN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
90 - -
Unknown (32651440)
GPS-Palm: 0.74
Deep-Palm: 0.86
114 DBPTM SWISSPALM Ribosomal Proteins L2 C-terminal domain -
Unknown (32651440)
GPS-Palm: 0.87
Deep-Palm: 0.98
115 - -
Unknown (32651440)
GPS-Palm: 0.89
Deep-Palm: 0.98
195 - - -
GPS-Palm: 0.87
Deep-Palm: 0.80
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.333
2
LNCaP
Specificity: 0.333
2/2 (100.0%)
2
cerebral cortex
Specificity: 0.333
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.167
1/1 (100.0%)
1
293T cell
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine