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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P63001 Rac1 Ras-related C3 botulinum toxin substrate … Mus musculus (Mouse) 192 aa

Protein Details: P63001 (Rac1)

Protein Information
AccessionP63001
Protein NamesRas-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene SymbolRac1
OrganismMus musculus (Mouse)
Length192 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQAIKCVVVG11DGAVGKTCLL21ISYTTNAFPG31EYIPTVFDNY41SANVMVDGKP
51-10051VNLGLWDTAG61QEDYDRLRPL71SYPQTDVFLI81CFSLVSPASF91ENVRAKWYPE
101-150101VRHHCPNTPI111ILVGTKLDLR121DDKDTIEKLK131EKKLTPITYP141QGLAMAKEIG
151-192151AVKYLECSAL161TQRGLKTVFD171EAIRAVLCPP181PVKKRKRKCL191LL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase
Brain (31311849)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.09
18 Ras family P-loop containing nucleoside triphosphate hydrolase Transforming protein P21 ras signature Small GTPase Small GTPase Rho
Brain (31311849)
-
GPS-Palm: 0.76
Deep-Palm: 0.97
81 - - -
Deep-Palm: 0.95
105 SWISSPALM DBPTM CYSMODDB Ras family
Liver (28526873)
Brain (31311849)
MLE (39008777)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.97
157 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
MLE (39008777)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.93
Deep-Palm: 0.98
178 SWISSPALM -
Brain (31311849)
brain (39008777)
MLE (39008777)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.94
Deep-Palm: 0.98
189 - - -
GPS-Palm: 0.97
Deep-Palm: 0.04
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.133
6/6 (100.0%)
5
Brain
Specificity: 0.111
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
34
Brain tissue (Mass)
Specificity: 0.756
34/56 (60.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine