Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P63017 | Hspa8 | Heat shock cognate 71 kDa … | Mus musculus (Mouse) | 646 aa |
Protein Details: P63017 (Hspa8)
Protein Information
| Accession | P63017 |
|---|---|
| Protein Names | Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) |
| Gene Symbol | Hspa8 |
| Organism | Mus musculus (Mouse) |
| Length | 646 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29575903 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSKGPAVGID11LGTTYSCVGV21FQHGKVEIIA31NDQGNRTTPS41YVAFTDTERL
51-10051IGDAAKNQVA61MNPTNTVFDA71KRLIGRRFDD81AVVQSDMKHW91PFMVVNDAGR
101-150101PKVQVEYKGE111TKSFYPEEVS121SMVLTKMKEI131AEAYLGKTVT141NAVVTVPAYF
151-200151NDSQRQATKD161AGTIAGLNVL171RIINEPTAAA181IAYGLDKKVG191AERNVLIFDL
201-250201GGGTFDVSIL211TIEDGIFEVK221STAGDTHLGG231EDFDNRMVNH241FIAEFKRKHK
251-300251KDISENKRAV261RRLRTACERA271KRTLSSSTQA281SIEIDSLYEG291IDFYTSITRA
301-350301RFEELNADLF311RGTLDPVEKA321LRDAKLDKSQ331IHDIVLVGGS341TRIPKIQKLL
351-400351QDFFNGKELN361KSINPDEAVA371YGAAVQAAIL381SGDKSENVQD391LLLLDVTPLS
401-450401LGIETAGGVM411TVLIKRNTTI421PTKQTQTFTT431YSDNQPGVLI441QVYEGERAMT
451-500451KDNNLLGKFE461LTGIPPAPRG471VPQIEVTFDI481DANGILNVSA491VDKSTGKENK
501-550501ITITNDKGRL511SKEDIERMVQ521EAEKYKAEDE531KQRDKVSSKN541SLESYAFNMK
551-600551ATVEDEKLQG561KINDEDKQKI571LDKCNEIISW581LDKNQTAEKE591EFEHQQKELE
601-646601KVCNPIITKL611YQSAGGMPGG621MPGGFPGGGA631PPSGGASSGP641TIEEVD
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | SWISSPALM DBPTM CYSMODDB | ATPase, nucleotide binding domain Heat shock protein 70 family 70kDa heat shock protein signature Hsp70 protein |
liver
(26165157)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.96
|
| 267 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.97
|
|
| 574 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.65
|
| 603 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.73
Deep-Palm: 0.90
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
5
Liver
Specificity: 0.109
5/5 (100.0%)
5
Brain
Specificity: 0.109
5/5 (100.0%)
2
Testis
Specificity: 0.043
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.022
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
33
Brain tissue (Mass)
Specificity: 0.717
33/56 (58.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.