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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P63101 Ywhaz 14-3-3 protein zeta/delta (Protein kinase … Mus musculus (Mouse) 245 aa

Protein Details: P63101 (Ywhaz)

Protein Information
AccessionP63101
Protein Names14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene SymbolYwhaz
OrganismMus musculus (Mouse)
Length245 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDKNELVQKA11KLAEQAERYD21DMAACMKSVT31EQGAELSNEE41RNLLSVAYKN
51-10051VVGARRSSWR61VVSSIEQKTE71GAEKKQQMAR81EYREKIETEL91RDICNDVLSL
101-150101LEKFLIPNAS111QPESKVFYLK121MKGDYYRYLA131EVAAGDDKKG141IVDQSQQAYQ
151-200151EAFEISKKEM161QPTHPIRLGL171ALNFSVFYYE181ILNSPEKACS191LAKTAFDEAI
201-245201AELDTLSEES211YKDSTLIMQL221LRDNLTLWTS231DTQGDEAEAG241EGGEN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
25 14-3-3 domain superfamily 14-3-3 domain 14-3-3 protein -
Brain (35358180)
GPS-Palm: 0.77
Deep-Palm: 0.90
94 SWISSPALM DBPTM CYSMODDB 14-3-3 protein
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.83
Deep-Palm: 0.97
189 - - -
GPS-Palm: 0.83
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
5
Liver
Specificity: 0.128
5/5 (100.0%)
3
Brain
Specificity: 0.077
3/3 (100.0%)
2
Testis
Specificity: 0.051
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
29
Brain tissue (Mass)
Specificity: 0.744
29/56 (51.8%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine