Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P63104-2 | YWHAZ | 14-3-3 protein zeta/delta (Protein kinase … | Homo sapiens (Human) | 170 aa |
Protein Details: P63104-2 (YWHAZ)
Protein Information
| Accession | P63104-2 |
|---|---|
| Protein Names | 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) |
| Gene Symbol | YWHAZ |
| Organism | Homo sapiens (Human) |
| Length | 170 aa |
| Isoforms | |
| Related PMIDs | 31251020 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSQPCRKLWR11HNYETSSCIE21FLKSLLEKFL31IPNASQAESK41VFYLKMKGDY
51-10051YRYLAEVAAG61DDKKGIVDQS71QQAYQEAFEI81SKKEMQPTHP91IRLGLALNFS
101-150101VFYYEILNSP111EKACSLAKTA121FDEAIAELDT131LSEESYKDST141LIMQLLRDNL
151-170151TLWTSDTQGD161EAEAGEGGEN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.91
|
|
| 25 | - | - | - |
Deep-Palm: 0.90
|
|
| 94 | - | - | - |
Deep-Palm: 0.97
|
|
| 189 | - | - | - |
Deep-Palm: 0.91
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
PC3
Specificity: 0.444
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
1
LNCaP
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 29 | V → Cfs*3 | 0.002976 | INS | Frame Shift Ins | KIRC |
| 94 | C → S | 0.002747 | SNP | Missense Mutation | LIHC |
| 127 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 169 | G → C | 0.003460 | SNP | Missense Mutation | CESC |