Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P63158 Hmgb1 High mobility group protein B1 … Mus musculus (Mouse) 215 aa

Protein Details: P63158 (Hmgb1)

Protein Information
AccessionP63158
Protein NamesHigh mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene SymbolHmgb1
OrganismMus musculus (Mouse)
Length215 aa
IsoformsNo isoforms
Related PMIDs 29733200 34884899 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MGKGDPKKPR11GKMSSYAFFV21QTCREEHKKK31HPDASVNFSE41FSKKCSERWK
51-10051TMSAKEKGKF61EDMAKADKAR71YEREMKTYIP81PKGETKKKFK91DPNAPKRPPS
101-150101AFFLFCSEYR111PKIKGEHPGL121SIGDVAKKLG131EMWNNTAADD141KQPYEKKAAK
151-200151LKEKYEKDIA161AYRAKGKPDA171AKKGVVKAEK181SKKKKEEEDD191EEDEEDEEEE
201-215201EEEEDEDEEE211DDDDE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
23 High Mobility Group Box (HMGB) High mobility group box domain High mobility group box domain superfamily -
Brain (35358180)
GPS-Palm: 0.66
Deep-Palm: 0.49
45 High Mobility Group Box (HMGB) HMG-box HMGB rpt1 High mobility group box domain superfamily High mobility group box domain - -
Deep-Palm: 0.46
106 SWISSPALM DBPTM CYSMODDB HMG (high mobility group) box -
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.91
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Liver
Specificity: 0.133
2/2 (100.0%)
1
Brain
Specificity: 0.067
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.800
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine