Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P63220 | RPS21 | Small ribosomal subunit protein eS21 … | Homo sapiens (Human) | 83 aa |
Protein Details: P63220 (RPS21)
Protein Information
| Accession | P63220 |
|---|---|
| Protein Names | Small ribosomal subunit protein eS21 (40S ribosomal protein S21) |
| Gene Symbol | RPS21 |
| Organism | Homo sapiens (Human) |
| Length | 83 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MQNDAGEFVD11LYVPRKCSAS21NRIIGAKDHA31SIQMNVAEVD41KVTGRFNGQF
51-8351KTYAICGAIR61RMGESDDSIL71RLAKADGIVS81KNF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 17 | Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS21 superfamily Small ribosomal subunit protein eS21, conserved site | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.76
|
|
| 56 | SWISSPALM DBPTM CYSMODDB | Ribosomal protein S21e | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
1
HAP1 cell
Specificity: 0.500
1/1 (100.0%)
1
293T cell
Specificity: 0.500
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | R → _C56del | 0.002288 | DEL | In Frame Del | STAD |
| 46 | F → C | 0.007299 | SNP | Missense Mutation | READ |
| 60 | R → C | 0.003460 | SNP | Missense Mutation | CESC |