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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P63244 RACK1; GNB2L1; HLC7; PIG21 Small ribosomal subunit protein RACK1 … Homo sapiens (Human) 317 aa

Protein Details: P63244 (RACK1)

Protein Information
Accession P63244
Protein Names Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene Symbol RACK1; GNB2L1; HLC7; PIG21
Organism Homo sapiens (Human)
Length 317 aa
Isoforms No isoforms
Related PMIDs 29575903 29733200 31251020 31382980 32944167 33636221 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.596
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
34
LNCaP cells
Specificity: 0.596
34/46 (73.9%)
10
HAP1 cells
Specificity: 0.175
10/10 (100.0%)
4
293T cells
Specificity: 0.070
4/10 (40.0%)
4
Cerebral cortex
Specificity: 0.070
4/4 (100.0%)
3
PC3 cells
Specificity: 0.053
3/4 (75.0%)
1
U937 cells
Specificity: 0.018
1/1 (100.0%)
1
Liver membrane
Specificity: 0.018
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MTEQMTLRGT11LKGHNGWVTQ21IATTPQFPDM31ILSASRDKTI41IMWKLTRDET
51-10051NYGIPQRALR61GHSHFVSDVV71ISSDGQFALS81GSWDGTLRLW91DLTTGTTTRR
101-150101FVGHTKDVLS111VAFSSDNRQI121VSGSRDKTIK131LWNTLGVCKY141TVQDESHSEW
151-200151VSCVRFSPNS161SNPIIVSCGW171DKLVKVWNLA181NCKLKTNHIG191HTGYLNTVTV
201-250201SPDGSLCASG211GKDGQAMLWD221LNEGKHLYTL231DGGDIINALC241FSPNRYWLCA
251-300251ATGPSIKIWD261LEGKIIVDEL271KQEVISTSSK281AEPPQCTSLA291WSADGQTLFA
301-317301GYTDNLVRVW311QVTIGTR
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
138 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) WD domain G-beta repeat 29575903
168 Prediction (Medium) - -
182 Prediction (High) - -
207 Prediction (Low) - -
240 Experimental CYSMODDB SWISSPALM DBPTM Prediction (Medium) WD domain G-beta repeat 29575903
249 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
88 R → C 0.001887 SNP Missense Mutation UCEC
88 R → C 0.003460 SNP Missense Mutation CESC
245 R → C 0.002141 SNP Missense Mutation SKCM