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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P63244 RACK1 Small ribosomal subunit protein RACK1 … Homo sapiens (Human) 317 aa

Protein Details: P63244 (RACK1)

Protein Information
AccessionP63244
Protein NamesSmall ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor for activated C kinase 1) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene SymbolRACK1
OrganismHomo sapiens (Human)
Length317 aa
IsoformsNo isoforms
Related PMIDs 22496122 29733200 31251020 31382980 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTEQMTLRGT11LKGHNGWVTQ21IATTPQFPDM31ILSASRDKTI41IMWKLTRDET
51-10051NYGIPQRALR61GHSHFVSDVV71ISSDGQFALS81GSWDGTLRLW91DLTTGTTTRR
101-150101FVGHTKDVLS111VAFSSDNRQI121VSGSRDKTIK131LWNTLGVCKY141TVQDESHSEW
151-200151VSCVRFSPNS161SNPIIVSCGW171DKLVKVWNLA181NCKLKTNHIG191HTGYLNTVTV
201-250201SPDGSLCASG211GKDGQAMLWD221LNEGKHLYTL231DGGDIINALC241FSPNRYWLCA
251-300251ATGPSIKIWD261LEGKIIVDEL271KQEVISTSSK281AEPPQCTSLA291WSADGQTLFA
301-317301GYTDNLVRVW311QVTIGTR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
138 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
SW480 cell line (26865113)
HeLa (29575903)
Unknown (32651440)
GPS-Palm: 0.88
Deep-Palm: 0.87
153 - - -
Deep-Palm: 0.13
168 - -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.86
Deep-Palm: 0.26
182 - -
cerebral cortex (36430497)
GPS-Palm: 0.94
Deep-Palm: 0.80
207 - -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.69
Deep-Palm: 0.78
240 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
HeLa (29575903)
Unknown (32651440)
GPS-Palm: 0.89
Deep-Palm: 0.59
249 - -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.85
Deep-Palm: 0.69
286 - - -
Deep-Palm: 0.84
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.308
4
cerebral cortex
Specificity: 0.250
4/4 (100.0%)
3
LNCaP
Specificity: 0.188
3/3 (100.0%)
2
HAP1 cell
Specificity: 0.125
2/2 (100.0%)
1
U937 cell
Specificity: 0.062
1/1 (100.0%)
1
EC cell
Specificity: 0.062
1/1 (100.0%)
1
293T cell
Specificity: 0.062
1/1 (100.0%)
1
heart
Specificity: 0.062
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Cerebral Cortex (Mass)
Specificity: 0.188
3/4 (75.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine