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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P68040 Rack1 Small ribosomal subunit protein RACK1 … Mus musculus (Mouse) 317 aa

Protein Details: P68040 (Rack1)

Protein Information
AccessionP68040
Protein NamesSmall ribosomal subunit protein RACK1 (12-3) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) (Receptor of activated protein kinase C 1) (p205) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene SymbolRack1
OrganismMus musculus (Mouse)
Length317 aa
IsoformsNo isoforms
Related PMIDs 28526873 29575903 29733200 34884899 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MTEQMTLRGT11LKGHNGWVTQ21IATTPQFPDM31ILSASRDKTI41IMWKLTRDET
51-10051NYGIPQRALR61GHSHFVSDVV71ISSDGQFALS81GSWDGTLRLW91DLTTGTTTRR
101-150101FVGHTKDVLS111VAFSSDNRQI121VSGSRDKTIK131LWNTLGVCKY141TVQDESHSEW
151-200151VSCVRFSPNS161SNPIIVSCGW171DKLVKVWNLA181NCKLKTNHIG191HTGYLNTVTV
201-250201SPDGSLCASG211GKDGQAMLWD221LNEGKHLYTL231DGGDIINALC241FSPNRYWLCA
251-300251ATGPSIKIWD261LEGKIIVDEL271KQEVISTSSK281AEPPQCTSLA291WSADGQTLFA
301-317301GYTDNLVRVW311QVTIGTR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
138 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.88
Deep-Palm: 0.87
153 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.13
168 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.86
Deep-Palm: 0.25
182 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.94
Deep-Palm: 0.81
207 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Brain (35358180)
GPS-Palm: 0.69
Deep-Palm: 0.77
240 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Liver (34884899)
Brain (35358180)
GPS-Palm: 0.89
Deep-Palm: 0.59
249 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
-
GPS-Palm: 0.85
Deep-Palm: 0.68
286 SWISSPALM DBPTM CYSMODDB WD domain G-beta repeat
Liver (28526873)
Forebrain (28680068)
Brain (35358180)
Deep-Palm: 0.85
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.162
6/6 (100.0%)
2
Raw 264.7
Specificity: 0.054
2/2 (100.0%)
2
Testis
Specificity: 0.054
2/2 (100.0%)
1
Brain
Specificity: 0.027
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.692
18
Brain tissue (Mass)
Specificity: 0.486
18/56 (32.1%)
8
Macrophage Raw 264.7 (Mass)
Specificity: 0.216
8/10 (80.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine