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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P68104 EEF1A1; EEF1A; EF1A; LENG7 Elongation factor 1-alpha 1 (EF-1-alpha-1) … Homo sapiens (Human) 462 aa

Protein Details: P68104 (EEF1A1)

Protein Information
Accession P68104
Protein Names Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene Symbol EEF1A1; EEF1A; EF1A; LENG7
Organism Homo sapiens (Human)
Length 462 aa
Isoforms No isoforms
Related PMIDs 21076176 25914232 26876311 29733200 31251020 37611173
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.579
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
33
LNCaP cells
Specificity: 0.579
33/46 (71.7%)
10
HAP1 cells
Specificity: 0.175
10/10 (100.0%)
6
Jurkat T cells
Specificity: 0.105
6/25 (24.0%)
4
293T cells
Specificity: 0.070
4/10 (40.0%)
3
CEMx174 cells
Specificity: 0.053
3/3 (100.0%)
1
Prefrontal cortex
Specificity: 0.018
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGKEKTHINI11VVIGHVDSGK21STTTGHLIYK31CGGIDKRTIE41KFEKEAAEMG
51-10051KGSFKYAWVL61DKLKAERERG71ITIDISLWKF81ETSKYYVTII91DAPGHRDFIK
101-150101NMITGTSQAD111CAVLIVAAGV121GEFEAGISKN131GQTREHALLA141YTLGVKQLIV
151-200151GVNKMDSTEP161PYSQKRYEEI171VKEVSTYIKK181IGYNPDTVAF191VPISGWNGDN
201-250201MLEPSANMPW211FKGWKVTRKD221GNASGTTLLE231ALDCILPPTR241PTDKPLRLPL
251-300251QDVYKIGGIG261TVPVGRVETG271VLKPGMVVTF281APVNVTTEVK291SVEMHHEALS
301-350301EALPGDNVGF311NVKNVSVKDV321RRGNVAGDSK331NDPPMEAAGF341TAQVIILNHP
351-400351GQISAGYAPV361LDCHTAHIAC371KFAELKEKID381RRSGKKLEDG391PKFLKSGDAA
401-450401IVDMVPGKPM411CVESFSDYPP421LGRFAVRDMR431QTVAVGVIKA441VDKKAAGAGK
451-462451VTKSAQKAQK461AK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
31 Prediction (Low) - -
111 Experimental Prediction (Low) Elongation factor Tu GTP binding domain 37611173
234 Experimental - 37611173
411 CYSMODDB SWISSPALM DBPTM GTP-eEF1A C-terminal domain-like -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
29 Y → C 0.001969 SNP Missense Mutation HNSC
167 Y → C 0.002288 SNP Missense Mutation STAD
214 W → C 0.002747 SNP Missense Mutation LIHC
291 S → C 0.004854 SNP Missense Mutation BLCA
370 C → C 0.002288 SNP Silent STAD
411 C → Lfs*3 0.001014 INS Frame Shift Ins BRCA
424 F → Cfs*3 0.002141 DEL Frame Shift Del SKCM
427 R → C 0.002141 SNP Missense Mutation SKCM