Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P68368 Tuba4a Tubulin alpha-4A chain (EC 3.6.5.-) … Mus musculus (Mouse) 448 aa

Protein Details: P68368 (Tuba4a)

Protein Information
AccessionP68368
Protein NamesTubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 4) (Alpha-tubulin isotype M-alpha-4) (Tubulin alpha-4 chain)
Gene SymbolTuba4a
OrganismMus musculus (Mouse)
Length448 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MRECISVHVG11QAGVQMGNAC21WELYCLEHGI31QPDGQMPSDK41TIGGGDDSFT
51-10051TFFCETGAGK61HVPRAVFVDL71EPTVIDEIRN81GPYRQLFHPE91QLITGKEDAA
101-150101NNYARGHYTI111GKEIIDPVLD121RIRKLSDQCT131GLQGFLVFHS141FGGGTGSGFT
151-200151SLLMERLSVD161YGKKSKLEFS171IYPAPQVSTA181VVEPYNSILT191THTTLEHSDC
201-250201AFMVDNEAIY211DICRRNLDIE221RPTYTNLNRL231ISQIVSSITA241SLRFDGALNV
251-300251DLTEFQTNLV261PYPRIHFPLA271TYAPVISAEK281AYHEQLSVAE291ITNACFEPAN
301-350301QMVKCDPRHG311KYMACCLLYR321GDVVPKDVNA331AIAAIKTKRS341IQFVDWCPTG
351-400351FKVGINYQPP361TVVPGGDLAK371VQRAVCMLSN381TTAIAEAWAR391LDHKFDLMYA
401-448401KRAFVHWYVG411EGMEEGEFSE421AREDMAALEK431DYEEVGIDSY441EDEDEGEE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
GPS-Palm: 0.94
Deep-Palm: 0.02
20 Tubulin/FtsZ, GTPase domain OS01G0282866 PROTEIN Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
Deep-Palm: 0.31
25 Alpha tubulin Tubulin/FtsZ, GTPase domain OS01G0282866 PROTEIN Tubulin/FtsZ, GTPase domain superfamily -
Brain (35358180)
Deep-Palm: 0.13
54 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.89
129 - -
Brain (35358180)
Deep-Palm: 0.70
200 - - -
Deep-Palm: 0.07
213 - - -
GPS-Palm: 0.79
Deep-Palm: 0.16
295 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Liver (34884899)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.23
305 Tubulin C-terminal domain
Brain (34200797)
-
Deep-Palm: 0.17
315 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Brain (34200797)
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.85
Deep-Palm: 0.59
316 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.93
Deep-Palm: 0.79
347 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Brain (31311849)
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.84
Deep-Palm: 0.41
376 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.545
6
Liver
Specificity: 0.102
6/6 (100.0%)
5
Brain
Specificity: 0.085
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
48
Brain tissue (Mass)
Specificity: 0.814
48/56 (85.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine