Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P70349 Hint1 Adenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) … Mus musculus (Mouse) 126 aa

Protein Details: P70349 (Hint1)

Protein Information
AccessionP70349
Protein NamesAdenosine 5'-monophosphoramidase HINT1 (EC 3.9.1.-) (Desumoylating isopeptidase HINT1) (EC 3.4.22.-) (Histidine triad nucleotide-binding protein 1) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1)
Gene SymbolHint1
OrganismMus musculus (Mouse)
Length126 aa
IsoformsNo isoforms
Related PMIDs 34200797 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MADEIAKAQV11AQPGGDTIFG21KIIRKEIPAK31IIFEDDRCLA41FHDISPQAPT
51-10051HFLVIPKKHI61SQISVADDDD71ESLLGHLMIV81GKKCAADLGL91KRGYRMVVNE
101-126101GADGGQSVYH111IHLHVLGGRQ121MNWPPG
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
38 Histidine triad (HIT) protein HIT-like superfamily HIT-like domain
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.90
84 SWISSPALM DBPTM CYSMODDB HIT domain
liver (26165157)
-
GPS-Palm: 0.91
Deep-Palm: 0.97
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
Brain
Specificity: 0.115
3/3 (100.0%)
3
Liver
Specificity: 0.115
3/3 (100.0%)
2
Testis
Specificity: 0.077
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
18
Brain tissue (Mass)
Specificity: 0.692
18/56 (32.1%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine