Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P70375 F7 Coagulation factor VII (EC 3.4.21.21) … Mus musculus (Mouse) 446 aa

Protein Details: P70375 (F7)

Protein Information
AccessionP70375
Protein NamesCoagulation factor VII (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Cleaved into: Factor VII light chain; Factor VII heavy chain]
Gene SymbolF7
OrganismMus musculus (Mouse)
Length446 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVPQAHGLLL11LCFLLQLQGP21LGTAVFITQE31EAHGVLHRQR41RANSLLEELW
51-10051PGSLERECNE61EQCSFEEARE71IFKSPERTKQ81FWIVYSDGDQ91CASNPCQNGG
101-150101TCQDHLKSYV111CFCLLDFEGR121NCEKSKNEQL131ICANENGDCD141QYCRDHVGTK
151-200151RTCSCHEDYT161LQPDEVSCKP171KVEYPCGRIP181VVEKRNSSSR191QGRIVGGNVC
201-250201PKGECPWQAV211LKINGLLLCG221AVLLDARWIV231TAAHCFDNIR241YWGNITVVMG
251-300251EHDFSEKDGD261EQVRRVTQVI271MPDKYIRGKI281NHDIALLRLH291RPVTFTDYVV
301-350301PLCLPEKSFS311ENTLARIRFS321RVSGWGQLLD331RGATALELMS341IEVPRLMTQD
351-400351CLEHAKHSSN361TPKITENMFC371AGYMDGTKDA381CKGDSGGPHA391THYHGTWYLT
401-446401GVVSWGEGCA411AIGHIGVYTR421VSQYIDWLVR431HMDSKLQVGV441FRLPLL
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
12 - - -
Deep-Palm: 0.56
58 - - -
Deep-Palm: 0.84
63 - - -
Deep-Palm: 0.58
91 - - -
Deep-Palm: 0.01
96 - - -
Deep-Palm: 0.01
102 - - -
Deep-Palm: 0.02
111 - - -
Deep-Palm: 0.03
113 - - -
Deep-Palm: 0.05
122 - - -
Deep-Palm: 0.05
132 - - -
Deep-Palm: 0.02
139 - - -
Deep-Palm: 0.03
143 - - -
Deep-Palm: 0.02
153 - - -
Deep-Palm: 0.02
155 - - -
Deep-Palm: 0.02
168 - - -
Deep-Palm: 0.05
176 - - -
Deep-Palm: 0.78
200 - - -
Deep-Palm: 0.74
205 - - -
Deep-Palm: 0.72
219 - - -
Deep-Palm: 0.81
235 - - -
Deep-Palm: 0.16
303 -
liver (26165157)
-
Deep-Palm: 0.94
351 - - -
Deep-Palm: 0.55
370 - - -
Deep-Palm: 0.05
381 - - -
Deep-Palm: 0.02
409 - - -
Deep-Palm: 0.14
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
10 C → C 0.001887 SNP Silent UCEC
72 S → C 0.005435 SNP Missense Mutation ESCA
170 R → C 0.001969 SNP Missense Mutation LGG
178 Y → C 0.001887 SNP Missense Mutation UCEC