Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P70441 | Nherf1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 … | Mus musculus (Mouse) | 355 aa |
Protein Details: P70441 (Nherf1)
Protein Information
| Accession | P70441 |
|---|---|
| Protein Names | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) |
| Gene Symbol | Nherf1 |
| Organism | Mus musculus (Mouse) |
| Length | 355 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSADAAAGEP11LPRLCCLEKG21PNGYGFHLHG31EKGKVGQFIR41LVEPGSPAEK
51-10051SGLLAGDRLV61EVNGENVEKE71THQQVVSRIR81AALNAVRLLV91VDPETDERLK
101-150101KLGVSIREEL111LRPQEKSEQA121EPPAAADTHE131AGDQNEAEKS141HLRELRPRLC
151-200151TMKKGPNGYG161FNLHSDKSKP171GQFIRAVDPD181SPAEASGLRA191QDRIVEVNGV
201-250201CMEGKQHGDV211VSAIKGGGDE221AKLLVVDKET231DEFFKKCKVI241PSQEHLDGPL
251-300251PEPFSNGEIQ261KESSREALVE271PASESPRPAL281ARSASSDTSE291ELNSQDSPKR
301-350301QVSTEPSSTS311SSSSDPILDL321NISLAVAKER331AHQKRSSKRA341PQMDWSKKNE
351-355351LFSNL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 15 | PDZ superfamily | - |
Brain
(35358180)
|
GPS-Palm: 0.84
Deep-Palm: 0.91
|
|
| 16 | PDZ superfamily | - |
Brain
(35358180)
|
GPS-Palm: 0.81
Deep-Palm: 0.94
|
|
| 150 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.81
|
|
| 201 | SWISSPALM DBPTM CYSMODDB | PDZ domain |
Liver
(28526873)
| - |
GPS-Palm: 0.83
Deep-Palm: 0.81
|
| 237 | - | - | - |
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
6
Liver
Specificity: 0.500
6/6 (100.0%)
2
Testis
Specificity: 0.167
2/2 (100.0%)
1
Brain
Specificity: 0.083
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.250
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.