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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P70694 Akr1c6 Estradiol 17 beta-dehydrogenase 5 (EC … Mus musculus (Mouse) 323 aa

Protein Details: P70694 (Akr1c6)

Protein Information
AccessionP70694
Protein NamesEstradiol 17 beta-dehydrogenase 5 (EC 1.1.1.-) (17-beta-HSD 5)
Gene SymbolAkr1c6
OrganismMus musculus (Mouse)
Length323 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDSKQQTVRL11SDGHFIPILG21FGTYAPQEVP31KSKATEATKI41AIDAGFRHID
51-10051SASMYQNEKE61VGLAIRSKIA71DGTVKREDIF81YTSKVWCTFH91RPELVRVCLE
101-150101QSLKQLQLDY111VDLYLIHFPM121AMKPGENYLP131KDENGKLIYD141AVDICDTWEA
151-200151MEKCKDAGLA161KSIGVSNFNR171RQLEKILKKP181GLKYKPVCNQ191VECHPYLNQG
201-250201KLLDFCRSKD211IVLVAYSALG221SHREKQWVDQ231SSPVLLDNPV241LGSMAKKYNR
251-300251TPALIALRYQ261LQRGVVVLAK271SFSEKRIKEN281MQVFEFQLTS291EDMKVLDDLN
301-323301KNIRYISGSS311FKDHPDFPFW321DEY
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
87 - - -
Deep-Palm: 0.67
98 SWISSPALM DBPTM CYSMODDB Aldo/keto reductase family
Liver (28526873)
-
GPS-Palm: 0.86
Deep-Palm: 0.78
145 - - -
Deep-Palm: 0.79
154 - - -
Deep-Palm: 0.46
188 SWISSPALM DBPTM CYSMODDB Aldo/keto reductase family
Liver (28526873)
-
GPS-Palm: 0.68
Deep-Palm: 0.91
193 SWISSPALM DBPTM CYSMODDB Aldo/keto reductase family
Liver (28526873)
-
GPS-Palm: 0.66
Deep-Palm: 0.71
206 - - -
GPS-Palm: 0.78
Deep-Palm: 0.95
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine