Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P80404 | ABAT | 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) … | Homo sapiens (Human) | 500 aa |
Protein Details: P80404 (ABAT)
Protein Information
| Accession | P80404 |
|---|---|
| Protein Names | 4-aminobutyrate aminotransferase, mitochondrial (EC 2.6.1.19) ((S)-3-amino-2-methylpropionate transaminase) (EC 2.6.1.22) (GABA aminotransferase) (GABA-AT) (Gamma-amino-N-butyrate transaminase) (GABA transaminase) (GABA-T) (L-AIBAT) |
| Gene Symbol | ABAT |
| Organism | Homo sapiens (Human) |
| Length | 500 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 33636221 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASMLLAQRL11ACSFQHSYRL21LVPGSRHISQ31AAAKVDVEFD41YDGPLMKTEV
51-10051PGPRSQELMK61QLNIIQNAEA71VHFFCNYEES81RGNYLVDVDG91NRMLDLYSQI
101-150101SSVPIGYSHP111ALLKLIQQPQ121NASMFVNRPA131LGILPPENFV141EKLRQSLLSV
151-200151APKGMSQLIT161MACGSCSNEN171ALKTIFMWYR181SKERGQRGFS191QEELETCMIN
201-250201QAPGCPDYSI211LSFMGAFHGR221TMGCLATTHS231KAIHKIDIPS241FDWPIAPFPR
251-300251LKYPLEEFVK261ENQQEEARCL271EEVEDLIVKY281RKKKKTVAGI291IVEPIQSEGG
301-350301DNHASDDFFR311KLRDIARKHG321CAFLVDEVQT331GGGCTGKFWA341HEHWGLDDPA
351-400351DVMTFSKKMM361TGGFFHKEEF371RPNAPYRIFN381TWLGDPSKNL391LLAEVINIIK
401-450401REDLLNNAAH411AGKALLTGLL421DLQARYPQFI431SRVRGRGTFC441SFDTPDDSIR
451-500451NKLILIARNK461GVVLGGCGDK471SIRFRPTLVF481RDHHAHLFLN491IFSDILADFK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 12 | - | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.25
|
|
| 75 | - | - | - |
Deep-Palm: 0.14
|
|
| 163 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.55
|
|
| 166 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.25
|
|
| 197 | - | - | - |
Deep-Palm: 0.61
|
|
| 205 | - | - | - |
Deep-Palm: 0.27
|
|
| 224 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.72
|
|
| 269 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
|
Deep-Palm: 0.97
|
|
| 321 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.89
Deep-Palm: 0.93
|
|
| 334 | - | - |
cerebral cortex
(36430497)
|
Deep-Palm: 0.58
|
|
| 440 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.80
Deep-Palm: 0.92
|
|
| 467 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.98
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
1
LNCaP
Specificity: 0.091
1/1 (100.0%)
1
heart
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Cerebral Cortex (Mass)
Specificity: 0.364
4/4 (100.0%)
1
LNCaP cells (Mass)
Specificity: 0.091
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 25 | S → C | 0.001014 | SNP | Missense Mutation | BRCA |
| 223 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |