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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P84095 RHOG Rho-related GTP-binding protein RhoG Homo sapiens (Human) 191 aa

Protein Details: P84095 (RHOG)

Protein Information
AccessionP84095
Protein NamesRho-related GTP-binding protein RhoG
Gene SymbolRHOG
OrganismHomo sapiens (Human)
Length191 aa
IsoformsNo isoforms
Related PMIDs 29733200 31251020 31382980 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQSIKCVVVG11DGAVGKTCLL21ICYTTNAFPK31EYIPTVFDNY41SAQSAVDGRT
51-10051VNLNLWDTAG61QEEYDRLRTL71SYPQTNVFVI81CFSIASPPSY91ENVRHKWHPE
101-150101VCHHCPDVPI111LLVGTKKDLR121AQPDTLRRLK131EQGQAPITPQ141QGQALAKQIH
151-191151AVRYLECSAL161QQDGVKEVFA171EAVRAVLNPT181PIKRGRSCIL191L
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 SWISSPALM DBPTM CYSMODDB Ras family P-loop containing nucleoside triphosphate hydrolase Small GTPase -
cerebral cortex (36430497)
GPS-Palm: 0.90
Deep-Palm: 0.08
18 Transforming protein P21 ras signature P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho -
Unknown (32651440)
GPS-Palm: 0.78
Deep-Palm: 0.96
22 Transforming protein P21 ras signature P-loop containing nucleoside triphosphate hydrolase Small GTPase Small GTPase Rho -
Unknown (32651440)
GPS-Palm: 0.92
Deep-Palm: 0.96
81 - - -
Deep-Palm: 0.39
102 - - -
Deep-Palm: 0.85
105 - - -
Deep-Palm: 0.90
157 - -
cerebral cortex (36430497)
Unknown (32651440)
GPS-Palm: 0.85
Deep-Palm: 0.98
188 - - -
GPS-Palm: 0.98
Deep-Palm: 0.04
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.300
3
PC3
Specificity: 0.214
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.214
3/3 (100.0%)
1
LNCaP
Specificity: 0.071
1/1 (100.0%)
1
HAP1 cell
Specificity: 0.071
1/1 (100.0%)
1
U937 cell
Specificity: 0.071
1/1 (100.0%)
1
293T cell
Specificity: 0.071
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.286
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
153 R → C 0.001887 SNP Missense Mutation UCEC