Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P84244 H3-3a;; H3-3b Histone H3.3 Mus musculus (Mouse) 136 aa

Protein Details: P84244 (H3-3a)

Protein Information
AccessionP84244
Protein NamesHistone H3.3
Gene SymbolH3-3a;; H3-3b
OrganismMus musculus (Mouse)
Length136 aa
IsoformsNo isoforms
Related PMIDs 28526873 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MARTKQTARK11STGGKAPRKQ21LATKAARKSA31PSTGGVKKPH41RYRPGTVALR
51-10051EIRRYQKSTE61LLIRKLPFQR71LVREIAQDFK81TDLRFQSAAI91GALQEASEAY
101-136101LVGLFEDTNL111CAIHAKRVTI121MPKDIQLARR131IRGERA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
111 SWISSPALM DBPTM CYSMODDB Core histone H2A/H2B/H3/H4 domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.84
Deep-Palm: 0.92
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 0.045
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
12
Brain tissue (Mass)
Specificity: 0.545
12/56 (21.4%)
9
Macrophage Raw 264.7 (Mass)
Specificity: 0.409
9/10 (90.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine