Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P97494 | Gclc; Glclc | Glutamate--cysteine ligase catalytic subunit (EC … | Mus musculus (Mouse) | 637 aa |
Protein Details: P97494 (Gclc)
Protein Information
| Accession | P97494 |
|---|---|
| Protein Names | Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) |
| Gene Symbol | Gclc; Glclc |
| Organism | Mus musculus (Mouse) |
| Length | 637 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 31772009 35477839 37925639 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.792
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.792
19/19 (100.0%)
3
Neural Stem Cells
Specificity: 0.125
3/3 (100.0%)
2
Testis
Specificity: 0.083
2/2 (100.0%)
0
Brain tissue
Specificity: 0.000
0/12 (0.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGLLSQGSPL11SWEETQRHAD21HVRRHGILQF31LHIYHAVKDR41HKDVLKWGDE
51-10051VEYMLVSFDH61ENRKVQLLLN71GGDVLETLQE81KGERTNPNHP91TLWRPEYGSY
101-150101MIEGTPGQPY111GGTMSEFNTV121EANMRKRRKE131ATSVLGEHQA141LCTITSFPRL
151-200151GCPGFTLPEH161RPNPEEGGAS171KSLFFPDEAI181NKHPRFGTLT191RNIRHRRGEK
201-250201VVINVPIFKD211KNTPSPFVET221FPEDAEASKA231SQPDHIYMDA241MGFGMGNCCL
251-300251QVTFQACSIS261EARYLYDQLA271TICPIVMALS281AASPFYRGYV291SDIDCRWGVI
301-350301SASVDDRTRE311ERGLEPLKNN321RFRISKSRYD331SIDSYLSKCG341EKYNDIDLTI
351-400351DKEIYEQLLE361EGIDHLLAQH371VAHLFIRDPL381TLFEEKIHLD391DANESDHFEN
401-450401IQSTNWQTMR411FKPPPPNSDI421GWRVEFRPME431VQLTDFENSA441YVVFVVLLTR
451-500451VILSYKLDFL461IPLSKVDENM471KVAQKRDAVL481QGMFYFRKDI491CKGGNAVVDG
501-550501CSKAQSSSEP511AAEEYTLMSI521DTIINGKEGV531FPGLIPILNS541YLENMEVDVD
551-600551TRCSILNYLK561LIKKRASGEL571MTVARWMREF581IANHPDYKQD591SVITDEINYS
601-637601LIWKCNQIAD611ELCECPELLG621SGFRKAKYSG631GKSDPSA
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 152 | Prediction (High) | - | - |
| 273 | Prediction (Low) | - | - |
| 295 | Experimental CYSMODDB SWISSPALM DBPTM | Glutamate-cysteine ligase | 28526873 |