Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
P99025 Gchfr GTP cyclohydrolase 1 feedback regulatory … Mus musculus (Mouse) 84 aa

Protein Details: P99025 (Gchfr)

Protein Information
AccessionP99025
Protein NamesGTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) (p35)
Gene SymbolGchfr
OrganismMus musculus (Mouse)
Length84 aa
IsoformsNo isoforms
Related PMIDs 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPYLLISTQI11RMEVGPTMVG21DEHSDPELMQ31HLGASKRSVL41GNNFYEYYVN
51-8451DPPRIVLDKL61ECKGFRVLSM71TGVGQTLVWC81LHKE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
62 SWISSPALM DBPTM CYSMODDB GTP cyclohydrolase I feedback regulatory protein (GFRP)
liver (26165157)
-
Deep-Palm: 0.96
80 - - -
GPS-Palm: 0.94
Deep-Palm: 0.02
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Liver
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine