Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| P99999 | CYCS | Cytochrome c | Homo sapiens (Human) | 105 aa |
Protein Details: P99999 (CYCS)
Protein Information
| Accession | P99999 |
|---|---|
| Protein Names | Cytochrome c |
| Gene Symbol | CYCS |
| Organism | Homo sapiens (Human) |
| Length | 105 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 31251020 33636221 36430497 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGDVEKGKKI11FIMKCSQCHT21VEKGGKHKTG31PNLHGLFGRK41TGQAPGYSYT
51-10051AANKNKGIIW61GEDTLMEYLE71NPKKYIPGTK81MIFVGIKKKE91ERADLIAYLK
101-105101KATNE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 15 | SWISSPALM DBPTM CYSMODDB | Cytochrome c Cytochrome c, class IA/ IB Cytochrome c-like domain superfamily Cytochrome c-like domain | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.76
|
| 18 | SWISSPALM DBPTM CYSMODDB | Cytochrome c Cytochrome c, class IA/ IB Cytochrome c-like domain superfamily Cytochrome c-like domain | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.375
3
LNCaP
Specificity: 0.375
3/3 (100.0%)
3
cerebral cortex
Specificity: 0.375
3/3 (100.0%)
1
heart
Specificity: 0.125
1/1 (100.0%)
1
HUVECs
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 18 | C → C | 0.001887 | SNP | Silent | UCEC |
| 60 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |