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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q01453 PMP22 Peripheral myelin protein 22 (PMP-22) … Homo sapiens (Human) 160 aa

Protein Details: Q01453 (PMP22)

Protein Information
AccessionQ01453
Protein NamesPeripheral myelin protein 22 (PMP-22) (Growth arrest-specific protein 3) (GAS-3)
Gene SymbolPMP22
OrganismHomo sapiens (Human)
Length160 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MLLLLLSIIV11LHVAVLVLLF21VSTIVSQWIV31GNGHATDLWQ41NCSTSSSGNV
51-10051HHCFSSSPNE61WLQSVQATMI71LSIIFSILSL81FLFFCQLFTL91TKGGRFYITG
101-150101IFQILAGLCV111MSAAAIYTVR121HPEWHLNSDY131SYGFAYILAW141VAFPLALLSG
151-160151VIYVILRKRE
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
42 PMP-22/EMP/MP20/Claudin - -
Deep-Palm: 0.04
53 - - -
Deep-Palm: 0.10
85 SWISSPALM DBPTM CYSMODDB PMP-22/EMP/MP20/Claudin family - -
GPS-Palm: 0.93
Deep-Palm: 0.91
109 - - -
Deep-Palm: 0.37
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
124 W → C 0.001764 SNP Missense Mutation LUAD
159 R → C 0.001969 SNP Missense Mutation HNSC
159 R → C 0.001887 SNP Missense Mutation UCEC