Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01469 | FABP5 | Fatty acid-binding protein 5 (Epidermal-type … | Homo sapiens (Human) | 135 aa |
Protein Details: Q01469 (FABP5)
Protein Information
| Accession | Q01469 |
|---|---|
| Protein Names | Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP) |
| Gene Symbol | FABP5 |
| Organism | Homo sapiens (Human) |
| Length | 135 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29733200 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATVQQLEGR11WRLVDSKGFD21EYMKELGVGI31ALRKMGAMAK41PDCIITCDGK
51-10051NLTIKTESTL61KTTQFSCTLG71EKFEETTADG81RKTQTVCNFT91DGALVQHQEW
101-135101DGKESTITRK111LKDGKLVVEC121VMNNVTCTRI131YEKVE
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 43 | Intracellular lipid binding protein Lipocalin/cytosolic fatty-acid binding domain Calycin | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.96
|
|
| 47 | Intracellular lipid binding protein Calycin | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.94
|
|
| 67 | SWISSPALM DBPTM CYSMODDB | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.76
Deep-Palm: 0.97
|
| 87 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.68
|
|
| 120 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.89
Deep-Palm: 0.95
|
|
| 127 | - | - |
Unknown
(32651440)
|
GPS-Palm: 0.72
Deep-Palm: 0.03
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.250
1
HAP1 cell
Specificity: 0.200
1/1 (100.0%)
1
293T cell
Specificity: 0.200
1/1 (100.0%)
1
cerebral cortex
Specificity: 0.200
1/1 (100.0%)
1
HUVECs
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Cerebral Cortex (Mass)
Specificity: 0.200
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 43 | C → C | 0.002033 | SNP | Silent | LUSC |