Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01628 | IFITM3 | Interferon-induced transmembrane protein 3 (Dispanin … | Homo sapiens (Human) | 133 aa |
Protein Details: Q01628 (IFITM3)
Protein Information
| Accession | Q01628 |
|---|---|
| Protein Names | Interferon-induced transmembrane protein 3 (Dispanin subfamily A member 2b) (DSPA2b) (Interferon-inducible protein 1-8U) |
| Gene Symbol | IFITM3 |
| Organism | Homo sapiens (Human) |
| Length | 133 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 24357059 26111759 29733200 31251020 33636221 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNHTVQTFFS11PVNSGQPPNY21EMLKEEHEVA31VLGAPHNPAP41PTSTVIHIRS
51-10051ETSVPDHVVW61SLFNTLFMNP71CCLGFIAFAY81SVKSRDRKMV91GDVTGAQAYA
101-133101STAKCLNIWA111LILGILMTIL121LIVIPVLIFQ131AYG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 71 | SWISSPALM DBPTM CYSMODDB | Interferon-induced transmembrane protein |
HeLa
(29575903)
| - |
GPS-Palm: 0.86
Deep-Palm: 0.70
|
| 72 | SWISSPALM DBPTM CYSMODDB | Interferon-induced transmembrane protein |
HeLa
(29575903)
| - |
GPS-Palm: 0.89
Deep-Palm: 0.74
|
| 105 | DBPTM SWISSPALM | Interferon-induced transmembrane protein | - | - |
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.250
2
LNCaP
Specificity: 0.250
2/2 (100.0%)
2
Primary T cell
Specificity: 0.250
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.125
1/1 (100.0%)
1
EC cell
Specificity: 0.125
1/1 (100.0%)
1
heart
Specificity: 0.125
1/1 (100.0%)
1
HUVECs
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 71 | C → Y | 0.002506 | SNP | Missense Mutation | COAD |