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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q01628 IFITM3 Interferon-induced transmembrane protein 3 (Dispanin … Homo sapiens (Human) 133 aa

Protein Details: Q01628 (IFITM3)

Protein Information
Accession Q01628
Protein Names Interferon-induced transmembrane protein 3 (Dispanin subfamily A member 2b) (DSPA2b) (Interferon-inducible protein 1-8U)
Gene Symbol IFITM3
Organism Homo sapiens (Human)
Length 133 aa
Isoforms No isoforms
Related PMIDs 22496122 24357059 26111759 29575903 29733200 31251020 32944167 33636221
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.419
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.419
13/46 (28.3%)
4
PC3 cells
Specificity: 0.129
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.129
4/10 (40.0%)
4
293T cells
Specificity: 0.129
4/10 (40.0%)
2
T cells
Specificity: 0.065
2/4 (50.0%)
2
Endothelial cells
Specificity: 0.065
2/2 (100.0%)
1
HeLa cells
Specificity: 0.032
1/1 (100.0%)
1
Liver membrane
Specificity: 0.032
1/1 (100.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNHTVQTFFS11PVNSGQPPNY21EMLKEEHEVA31VLGAPHNPAP41PTSTVIHIRS
51-10051ETSVPDHVVW61SLFNTLFMNP71CCLGFIAFAY81SVKSRDRKMV91GDVTGAQAYA
101-133101STAKCLNIWA111LILGILMTIL121LIVIPVLIFQ131AYG
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
71 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Interferon-induced transmembrane protein -
72 CYSMODDB SWISSPALM DBPTM Prediction (Medium) Interferon-induced transmembrane protein -
105 DBPTM SWISSPALM Interferon-induced transmembrane protein -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
71 C → Y 0.002506 SNP Missense Mutation COAD