Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01629 | IFITM2 | Interferon-induced transmembrane protein 2 (Dispanin … | Homo sapiens (Human) | 132 aa |
Protein Details: Q01629 (IFITM2)
Protein Information
| Accession | Q01629 |
|---|---|
| Protein Names | Interferon-induced transmembrane protein 2 (Dispanin subfamily A member 2c) (DSPA2c) (Interferon-inducible protein 1-8D) |
| Gene Symbol | IFITM2 |
| Organism | Homo sapiens (Human) |
| Length | 132 aa |
| Isoforms | No isoforms |
| Related PMIDs | 22496122 26111759 31251020 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNHIVQTFSP11VNSGQPPNYE21MLKEEQEVAM31LGVPHNPAPP41MSTVIHIRSE
51-10051TSVPDHVVWS61LFNTLFMNTC71CLGFIAFAYS81VKSRDRKMVG91DVTGAQAYAS
101-132101TAKCLNIWAL111ILGIFMTILL121IIIPVLVVQA131QR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 70 | DBPTM SWISSPALM | Interferon-induced transmembrane protein | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.62
|
| 71 | DBPTM SWISSPALM | Interferon-induced transmembrane protein | - | - |
GPS-Palm: 0.87
Deep-Palm: 0.54
|
| 104 | - | - | - |
Deep-Palm: 0.95
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
2
LNCaP
Specificity: 0.400
2/2 (100.0%)
2
Jurkat T cell
Specificity: 0.400
2/2 (100.0%)
1
EC cell
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 83 | S → C | 0.002288 | SNP | Missense Mutation | STAD |