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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q01629 IFITM2 Interferon-induced transmembrane protein 2 (Dispanin … Homo sapiens (Human) 132 aa

Protein Details: Q01629 (IFITM2)

Protein Information
Accession Q01629
Protein Names Interferon-induced transmembrane protein 2 (Dispanin subfamily A member 2c) (DSPA2c) (Interferon-inducible protein 1-8D)
Gene Symbol IFITM2
Organism Homo sapiens (Human)
Length 132 aa
Isoforms No isoforms
Related PMIDs 22496122 26111759 29575903 31251020
Database Sources dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.722
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
13
LNCaP cells
Specificity: 0.722
13/46 (28.3%)
3
Jurkat T cells
Specificity: 0.167
3/25 (12.0%)
1
HeLa cells
Specificity: 0.056
1/1 (100.0%)
1
Endothelial cells
Specificity: 0.056
1/2 (50.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MNHIVQTFSP11VNSGQPPNYE21MLKEEQEVAM31LGVPHNPAPP41MSTVIHIRSE
51-10051TSVPDHVVWS61LFNTLFMNTC71CLGFIAFAYS81VKSRDRKMVG91DVTGAQAYAS
101-132101TAKCLNIWAL111ILGIFMTILL121IIIPVLVVQA131QR
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
70 DBPTM SWISSPALM Prediction (Medium) Interferon-induced transmembrane protein -
71 DBPTM SWISSPALM Prediction (Medium) Interferon-induced transmembrane protein -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
83 S → C 0.002288 SNP Missense Mutation STAD