Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01726 | MC1R | Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin … | Homo sapiens (Human) | 317 aa |
Protein Details: Q01726 (MC1R)
Protein Information
| Accession | Q01726 |
|---|---|
| Protein Names | Melanocyte-stimulating hormone receptor (MSH-R) (Melanocortin receptor 1) (MC1-R) |
| Gene Symbol | MC1R |
| Organism | Homo sapiens (Human) |
| Length | 317 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | PTMDdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAVQGSQRRL11LGSLNSTPTA21IPQLGLAANQ31TGARCLEVSI41SDGLFLSLGL
51-10051VSLVENALVV61ATIAKNRNLH71SPMYCFICCL81ALSDLLVSGS91NVLETAVILL
101-150101LEAGALVARA111AVLQQLDNVI121DVITCSSMLS131SLCFLGAIAV141DRYISIFYAL
151-200151RYHSIVTLPR161ARRAVAAIWV171ASVVFSTLFI181AYYDHVAVLL191CLVVFFLAML
201-250201VLMAVLYVHM211LARACQHAQG221IARLHKRQRP231VHQGFGLKGA241VTLTILLGIF
251-300251FLCWGPFFLH261LTLIVLCPEH271PTCGCIFKNF281NLFLALIICN291AIIDPLIYAF
301-317301HSQELRRTLK311EVLTCSW
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | - | - | - |
Deep-Palm: 0.98
|
|
| 75 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.32
|
|
| 78 | - | - | - |
Deep-Palm: 0.22
|
|
| 79 | - | - | - |
Deep-Palm: 0.23
|
|
| 125 | - | - | - |
Deep-Palm: 0.86
|
|
| 133 | - | - | - |
GPS-Palm: 0.77
Deep-Palm: 0.15
|
|
| 191 | - | - | - |
Deep-Palm: 0.29
|
|
| 215 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.91
|
|
| 253 | - | - | - |
Deep-Palm: 0.34
|
|
| 267 | - | - | - |
Deep-Palm: 0.10
|
|
| 273 | - | - | - |
Deep-Palm: 0.28
|
|
| 275 | - | - | - |
Deep-Palm: 0.12
|
|
| 289 | - | - | - |
Deep-Palm: 0.15
|
|
| 315 | PTMD DBPTM SWISSPALM | - | - | - |
GPS-Palm: 0.99
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 35 | C → C | 0.002545 | SNP | Silent | GBM |
| 79 | C → Y | 0.010870 | SNP | Missense Mutation | ACC |
| 273 | C → C | 0.001887 | SNP | Silent | UCEC |