Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q01813-2 PFKP ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) … Homo sapiens (Human) 776 aa

Protein Details: Q01813-2 (PFKP)

Protein Information
AccessionQ01813-2
Protein NamesATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase)
Gene SymbolPFKP
OrganismHomo sapiens (Human)
Length776 aa
Isoforms
Related PMIDs 33636221 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MCGYERCRPC11RGAHGYLRGG21QGVLHLRGLP31GHGGRRLKHR41RGRLGECLQH
51-10051PASGAVRGDW61REKPGCWSHR71FPCPGRHALV81GGTIIGSARC91QAFRTREGRL
101-150101KAACNLLQRG111ITNLCVIGGD121GSLTGANLFR131KEWSGLLEEL141ARNGQIDKEA
151-200151VQKYAYLNVV161GMVGSIDNDF171CGTDMTIGTD181SALHRIIEVV191DAIMTTAQSH
201-250201QRTFVLEVMG211RHCGYLALVS221ALACGADWVF231LPESPPEEGW241EEQMCVKLSE
251-300251NRARKKRLNI261IIVAEGAIDT271QNKPITSEKI281KELVVTQLGY291DTRVTILGHV
301-350301QRGGTPSAFD311RILASRMGVE321AVIALLEATP331DTPACVVSLN341GNHAVRLPLM
351-400351ECVQMTQDVQ361KAMDERRFQD371AVRLRGRSFA381GNLNTYKRLA391IKLPDDQIPK
401-450401TNCNVAVINV411GAPAAGMNAA421VRSAVRVGIA431DGHRMLAIYD441GFDGFAKGQI
451-500451KEIGWTDVGG461WTGQGGSILG471TKRVLPGKYL481EEIATQMRTH491SINALLIIGG
501-550501FEAYLGLLEL511SAAREKHEEF521CVPMVMVPAT531VSNNVPGSDF541SIGADTALNT
551-600551ITDTCDRIKQ561SASGTKRRVF571IIETMGGYCG581YLANMGGLAA591GADAAYIFEE
601-650601PFDIRDLQSN611VEHLTEKMKT621TIQRGLVLRN631ESCSENYTTD641FIYQLYSEEG
651-700651KGVFDCRKNV661LGHMQQGGAP671SPFDRNFGTK681ISARAMEWIT691AKLKEARGRG
701-750701KKFTTDDSIC711VLGISKRNVI721FQPVAELKKQ731TDFEHRIPKE741QWWLKLRPLM
751-776751KILAKYKASY761DVSDSGQLEH771VQPWSV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
2 - - -
GPS-Palm: 0.92
7 - - -
GPS-Palm: 0.86
10 - - -
GPS-Palm: 0.73
47 - - -
GPS-Palm: 0.83
90 - - -
GPS-Palm: 0.83
98 - - -
Deep-Palm: 0.96
104 - - -
GPS-Palm: 0.97
112 - - -
Deep-Palm: 0.97
115 -
HeLa (29575903)
-
GPS-Palm: 0.82
123 - - -
Deep-Palm: 0.97
171 - - -
GPS-Palm: 0.72
179 - - -
Deep-Palm: 0.22
213 - - -
GPS-Palm: 0.66
221 - - -
Deep-Palm: 0.84
232 - - -
Deep-Palm: 0.96
253 - - -
Deep-Palm: 0.93
343 - - -
Deep-Palm: 0.96
352 - - -
GPS-Palm: 0.85
360 - - -
Deep-Palm: 0.69
411 - - -
Deep-Palm: 0.89
529 - - -
Deep-Palm: 0.85
555 - - -
GPS-Palm: 0.81
563 - - -
Deep-Palm: 0.80
579 - - -
GPS-Palm: 0.70
587 - - -
Deep-Palm: 0.93
633 - - -
GPS-Palm: 0.70
641 - - -
Deep-Palm: 0.66
664 - - -
Deep-Palm: 0.54
710 - - -
GPS-Palm: 0.87
718 - - -
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
cerebral cortex
Specificity: 0.800
4/4 (100.0%)
1
heart
Specificity: 0.200
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
44 R → C 0.002506 SNP Missense Mutation COAD
44 R → C 0.002141 SNP Missense Mutation SKCM
48 R → C 0.002288 SNP Missense Mutation STAD
48 R → C 0.002506 SNP Missense Mutation COAD
48 R → C 0.001887 SNP Missense Mutation UCEC
117 R → C 0.002288 SNP Missense Mutation STAD
118 G → C 0.002033 SNP Missense Mutation LUSC
343 C → C 0.004577 SNP Silent STAD
354 R → C 0.002288 SNP Missense Mutation STAD
354 R → C 0.001887 SNP Missense Mutation UCEC
440 G → C 0.001887 SNP Missense Mutation UCEC
563 C → C 0.001887 SNP Silent UCEC
576 R → C 0.002288 SNP Missense Mutation STAD