Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01853 | Vcp | Transitional endoplasmic reticulum ATPase (TER … | Mus musculus (Mouse) | 806 aa |
Protein Details: Q01853 (Vcp)
Protein Information
| Accession | Q01853 |
|---|---|
| Protein Names | Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP) |
| Gene Symbol | Vcp |
| Organism | Mus musculus (Mouse) |
| Length | 806 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MASGADSKGD11DLSTAILKQK21NRPNRLIVDE31AINEDNSVVS41LSQPKMDELQ
51-10051LFRGDTVLLK61GKKRREAVCI71VLSDDTCSDE81KIRMNRVVRN91NLRVRLGDVI
101-150101SIQPCPDVKY111GKRIHVLPID121DTVEGITGNL131FEVYLKPYFL141EAYRPIRKGD
151-200151IFLVRGGMRA161VEFKVVETDP171SPYCIVAPDT181VIHCEGEPIK191REDEEESLNE
201-250201VGYDDIGGCR211KQLAQIKEMV221ELPLRHPALF231KAIGVKPPRG241ILLYGPPGTG
251-300251KTLIARAVAN261ETGAFFFLIN271GPEIMSKLAG281ESESNLRKAF291EEAEKNAPAI
301-350301IFIDELDAIA311PKREKTHGEV321ERRIVSQLLT331LMDGLKQRAH341VIVMAATNRP
351-400351NSIDPALRRF361GRFDREVDIG371IPDATGRLEI381LQIHTKNMKL391ADDVDLEQVA
401-450401NETHGHVGAD411LAALCSEAAL421QAIRKKMDLI431DLEDETIDAE441VMNSLAVTMD
451-500451DFRWALSQSN461PSALRETVVE471VPQVTWEDIG481GLEDVKRELQ491ELVQYPVEHP
501-550501DKFLKFGMTP511SKGVLFYGPP521GCGKTLLAKA531IANECQANFI541SIKGPELLTM
551-600551WFGESEANVR561EIFDKARQAA571PCVLFFDELD581SIAKARGGNI591GDGGGAADRV
601-650601INQILTEMDG611MSTKKNVFII621GATNRPDIID631PAILRPGRLD641QLIYIPLPDE
651-700651KSRVAILKAN661LRKSPVAKDV671DLEFLAKMTN681GFSGADLTEI691CQRACKLAIR
701-750701ESIESEIRRE711RERQTNPSAM721EVEEDDPVPE731IRRDHFEEAM741RFARRSVSDN
751-800751DIRKYEMFAQ761TLQQSRGFGS771FRFPSGNQGG781AGPSQGSGGG791TGGSVYTEDN
801-806801DDDLYG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 69 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.79
Deep-Palm: 0.94
|
|
| 77 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.69
Deep-Palm: 0.81
|
|
| 105 | SWISSPALM DBPTM CYSMODDB | Cell division protein 48 (CDC48) N-terminal domain |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.94
Deep-Palm: 0.91
|
| 174 | Cell division protein 48 (CDC48) domain 2 |
Brain
(34200797)
| - |
Deep-Palm: 0.48
|
|
| 184 | Cell division protein 48 (CDC48) domain 2 |
Brain
(34200797)
| - |
GPS-Palm: 0.69
Deep-Palm: 0.75
|
|
| 209 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
GPS-Palm: 0.78
Deep-Palm: 0.84
|
| 415 | SWISSPALM DBPTM CYSMODDB | AAA+ lid domain |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.87
Deep-Palm: 0.97
|
| 522 | SWISSPALM DBPTM CYSMODDB | Holliday junction DNA helicase RuvB P-loop domain ATPase family associated with various cellular activities (AAA) |
MLE
(39008777)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.94
Deep-Palm: 0.97
|
| 535 | SWISSPALM DBPTM CYSMODDB | Holliday junction DNA helicase RuvB P-loop domain ATPase family associated with various cellular activities (AAA) |
MLE
(39008777)
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.85
Deep-Palm: 0.98
|
| 572 | SWISSPALM DBPTM CYSMODDB | ATPase family associated with various cellular activities (AAA) |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.92
Deep-Palm: 0.97
|
| 691 | SWISSPALM DBPTM CYSMODDB | AAA+ lid domain |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.94
Deep-Palm: 0.96
|
| 695 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
6
Liver
Specificity: 0.143
6/6 (100.0%)
6
Brain
Specificity: 0.143
6/6 (100.0%)
2
Testis
Specificity: 0.048
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
28
Brain tissue (Mass)
Specificity: 0.667
28/56 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.