Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01860 | POU5F1 | POU domain, class 5, transcription … | Homo sapiens (Human) | 360 aa |
Protein Details: Q01860 (POU5F1)
Protein Information
| Accession | Q01860 |
|---|---|
| Protein Names | POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) |
| Gene Symbol | POU5F1 |
| Organism | Homo sapiens (Human) |
| Length | 360 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | PTMDSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAGHLASDFA11FSPPPGGGGD21GPGGPEPGWV31DPRTWLSFQG41PPGGPGIGPG
51-10051VGPGSEVWGI61PPCPPPYEFC71GGMAYCGPQV81GVGLVPQGGL91ETSQPEGEAG
101-150101VGVESNSDGA111SPEPCTVTPG121AVKLEKEKLE131QNPEESQDIK141ALQKELEQFA
151-200151KLLKQKRITL161GYTQADVGLT171LGVLFGKVFS181QTTICRFEAL191QLSFKNMCKL
201-250201RPLLQKWVEE211ADNNENLQEI221CKAETLVQAR231KRKRTSIENR241VRGNLENLFL
251-300251QCPKPTLQQI261SHIAQQLGLE271KDVVRVWFCN281RRQKGKRSSS291DYAQREDFEA
301-350301AGSPFSGGPV311SFPLAPGPHF321GTPGYGSPHF331TALYSSVPFP341EGEAFPPVSV
351-360351TTLGSPMHSN
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 63 | - | - | - |
Deep-Palm: 0.18
|
|
| 70 | - | - | - |
Deep-Palm: 0.17
|
|
| 76 | - | - | - |
Deep-Palm: 0.49
|
|
| 115 | - | - | - |
Deep-Palm: 0.94
|
|
| 185 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.83
|
|
| 198 | PTMD | Pou domain - N-terminal to homeobox domain | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.94
|
| 221 | - | - | - |
Deep-Palm: 0.82
|
|
| 252 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.67
|
|
| 279 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.84
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
HAP1 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 76 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 198 | C → R | 0.002545 | SNP | Missense Mutation | GBM |
| 252 | C → F | 0.001764 | SNP | Missense Mutation | LUAD |