Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q01995 | TAGLN | Transgelin (22 kDa actin-binding protein) … | Homo sapiens (Human) | 201 aa |
Protein Details: Q01995 (TAGLN)
Protein Information
| Accession | Q01995 |
|---|---|
| Protein Names | Transgelin (22 kDa actin-binding protein) (Protein WS3-10) (Smooth muscle protein 22-alpha) (SM22-alpha) |
| Gene Symbol | TAGLN |
| Organism | Homo sapiens (Human) |
| Length | 201 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MANKGPSYGM11SREVQSKIEK21KYDEELEERL31VEWIIVQCGP41DVGRPDRGRL
51-10051GFQVWLKNGV61ILSKLVNSLY71PDGSKPVKVP81ENPPSMVFKQ91MEQVAQFLKA
101-150101AEDYGVIKTD111MFQTVDLFEG121KDMAAVQRTL131MALGSLAVTK141NDGHYRGDPN
151-200151WFMKKAQEHK161REFTESQLQE171GKHVIGLQMG181SNRGASQAGM191TGYGRPRQII
201-201201S
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 38 | SWISSPALM DBPTM CYSMODDB | Calponin-like CH domain superfamily |
HeLa
(29575903)
| - |
GPS-Palm: 0.88
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 135 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |