Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q02257 | Jup | Junction plakoglobin (Desmoplakin III) (Desmoplakin-3) | Mus musculus (Mouse) | 745 aa |
Protein Details: Q02257 (Jup)
Protein Information
| Accession | Q02257 |
|---|---|
| Protein Names | Junction plakoglobin (Desmoplakin III) (Desmoplakin-3) |
| Gene Symbol | Jup |
| Organism | Mus musculus (Mouse) |
| Length | 745 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 31311849 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MEVMNLIEQP11IKVTEWQQTY21TYDSGIHSGV31NTCVPSVSSK41GIMDEDDACG
51-10051RQYTLKKTTT61YTQGVPQNQG71DLEYQMSTTA81RAKRVREAMC91PGVSGEDSSL
101-150101LLATQVEGQT111TNLQRLAEPS121QLLKSAIVHL131INYQDDAELA141TRALPELTKL
151-200151LNDEDPVVVT161KAAMIVNQLS171KKEASRRALM181GSPQLVAAVV191RTMQNTSDLD
201-250201TARCTTSILH211NLSHHREGLL221AIFKSGGIPA231LVRMLSSPVE241SVLFYAITTL
251-300251HNLLLYQEGA261KMAVRLADGL271QKMVPLLNKN281NPKFLAITTD291CLQLLAYGNQ
301-350301ESKLIILANG311GPQGLVQIMR321NYSYEKLLWT331TSRVLKVLSV341CPSNKPAIVE
351-400351AGGMQALGKH361LTSNSPRLVQ371NCLWTLRNLS381DVATKQEGLE391SVLKILVNQL
401-450401SVDDVNVLTC411ATGTLSNLTC421NNSKNKTLVT431QNSGVEALIH441AILRAGDKDD
451-500451ITEPAVCALR461HLTSRHPEAE471MAQNSVRLNY481GIPAIVKLLN491QPNQWPLVKA
501-550501TIGLIRNLAL511CPANHAPLQE521AAVIPRLVQL531LVKAHQDAQR541HVAAGTQQPY
551-600551TDGVRMEEIV561EGCTGALHIL571ARDPMNRMEI581FRLNTIPLFV591QLLYSSVENI
601-650601QRVAAGVLCE611LAQDKEAADA621IDAEGASAPL631MELLHSRNEG641TATYAAAVLF
651-700651RISEDKNPDY661RKRVSVELTN671SLFKHDPAAW681EAAQSMIPIN691EPYADDMDAT
701-745701YRPMYSSDVP711LDPLDMHMDL721DGDYPMDTYS731DGLRPPYPTA741DHMLA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 33 | - | - | - |
GPS-Palm: 0.67
Deep-Palm: 0.15
|
|
| 49 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.70
|
|
| 90 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 204 | - | - | - |
Deep-Palm: 0.52
|
|
| 291 | - | - | - |
Deep-Palm: 0.81
|
|
| 341 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 372 | - | - |
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.91
Deep-Palm: 0.92
|
|
| 410 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.81
|
|
| 420 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.78
Deep-Palm: 0.91
|
|
| 457 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
liver
(26165157)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.88
Deep-Palm: 0.95
|
| 511 | - | - |
Brain
(35358180)
|
GPS-Palm: 0.89
Deep-Palm: 0.98
|
|
| 563 | - | - |
Liver
(34884899)
Brain
(35358180)
|
GPS-Palm: 0.92
Deep-Palm: 0.77
|
|
| 609 | - | - |
Brain
(35358180)
Macrophage Raw 264.7
(29217618)
Brain
(31311849)
|
GPS-Palm: 0.90
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
5
Liver
Specificity: 0.172
5/5 (100.0%)
3
Brain
Specificity: 0.103
3/3 (100.0%)
2
Testis
Specificity: 0.069
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.632
12
Brain tissue (Mass)
Specificity: 0.414
12/56 (21.4%)
7
Macrophage Raw 264.7 (Mass)
Specificity: 0.241
7/10 (70.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.